{"id":"W1917240678","doi":"10.4049/jimmunol.0800680","title":"Disseminated and Rapidly Fatal Tuberculosis in Mice Bearing a Defective Allele at IFN Regulatory Factor 8","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Mycobacterium tuberculosis; Biology; Tuberculosis; Interferon regulatory factors; Immunology; IRF1; Immunity; Allele; Priming (agriculture); Interferon gamma; Virology; Immune system; Gene; Medicine; Transcription factor; Genetics; Innate immune system; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003055828,0.001210791,0.000552102,0.0008808518,0.0003527722,0.0005435421,0.0003216996,0.001104371,0.002575168],"category_scores_gemma":[0.000306416,0.0006680934,0.0003563027,0.0001994323,0.0006456292,0.000435804,0.0003559052,0.00167252,0.0007757698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004177588,"about_ca_system_score_gemma":0.0002226848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005618219,"about_ca_topic_score_gemma":0.0005149041,"domain_scores_codex":[0.9996533,0.00007372991,0.00003576638,0.00008770861,0.00005506144,0.00009446869],"domain_scores_gemma":[0.9992473,0.0001042696,0.0002908472,0.00007951587,0.0000312282,0.0002468236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006073926,0.0002203028,0.0005784229,0.00002619077,0.000008285811,0.0004166147,0.00003021263,0.00008535783,0.9970764,0.0001583373,0.00005767003,0.0007347349],"study_design_scores_gemma":[0.001254245,0.009742511,0.04049171,0.0001058554,0.0001312693,0.01321549,0.0002529923,0.00437715,0.9261585,0.0007711895,0.003428318,0.00007067039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968293,0.0004512538,0.001137636,0.0001299374,0.00002706448,0.00003955968,0.0005329756,0.0001371175,0.0007150372],"genre_scores_gemma":[0.9936068,0.0004195622,0.001453975,0.000112426,0.00002617174,0.00005899277,0.0007604516,0.00008271579,0.003478871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002575168,"threshold_uncertainty_score":0.008614779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498039481180539,"score_gpt":0.2938081458216144,"score_spread":0.2788277510098089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}