{"id":"W1917301047","doi":"10.1242/jcs.113.12.2221","title":"Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBFα/AML/PEBP2α) dependent activation of tissue-specific gene transcription","year":2000,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Biology; Transcription factor; Gene; Genetics; Transcription (linguistics); Cell biology; Nuclear matrix; Chromatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005346927,0.00008820862,0.0001107663,0.0000449501,0.0001574922,0.00006412275,0.0003149286,0.00005047384,0.00004746742],"category_scores_gemma":[0.00002155612,0.00005867294,0.00004036941,0.0001424468,0.0002370958,0.00003385456,0.00002227086,0.00009895373,0.000001609713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003013757,"about_ca_system_score_gemma":0.0001012187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008896292,"about_ca_topic_score_gemma":0.000003155624,"domain_scores_codex":[0.998929,0.00005597562,0.0002292298,0.0001840741,0.0004468879,0.0001548009],"domain_scores_gemma":[0.9992539,0.00001085368,0.0003006757,0.0001861607,0.0001690689,0.00007939198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002099672,0.00007479956,0.0001457606,0.00001039961,0.000009920089,0.0000028161,0.0002645987,0.00055917,0.9958149,0.000006408306,0.00008776621,0.002813467],"study_design_scores_gemma":[0.0004142149,0.0003817889,0.006662219,0.00002917907,0.00002002725,0.00002979524,0.000102613,0.0000278037,0.9862946,0.00002105458,0.00593557,0.00008112918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978924,0.0007608593,0.0007219763,0.0001551283,0.00003722008,0.0001483376,0.00000342444,0.000003098725,0.0002775024],"genre_scores_gemma":[0.9981182,0.0001939818,0.001173889,0.00002926118,0.0001006178,0.000001899891,0.000001153148,0.000009862989,0.0003711735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009520321,"threshold_uncertainty_score":0.2392613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00695805999695492,"score_gpt":0.227413032906287,"score_spread":0.2204549729093321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}