{"id":"W1918015637","doi":"","title":"Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.","year":2005,"lang":"en","type":"article","venue":"PubMed","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital du Sacré-Cœur de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Leukotriene B4; Naproxen; Cyclooxygenase; Prostaglandin E2; Leukotriene; Leukotriene C4; Pharmacology; Chemistry; Arachidonic acid; Synovial membrane; Arachidonate 5-lipoxygenase; Prostaglandin; Eicosanoid; Lipopolysaccharide; Internal medicine; Inflammation; Biochemistry; Medicine; Enzyme; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002226744,0.0005114363,0.0002466434,0.0002996478,0.00024053,0.0003975995,0.0001387237,0.0003558867,0.002064218],"category_scores_gemma":[0.0002571403,0.0001550557,0.0002680084,0.0002172899,0.000265088,0.0005085092,0.0002391062,0.0003442478,0.000558964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003448874,"about_ca_system_score_gemma":0.0003098705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004475114,"about_ca_topic_score_gemma":0.0005477998,"domain_scores_codex":[0.9998468,0.00004344732,0.00001634624,0.00002705848,0.0000321931,0.00003418888],"domain_scores_gemma":[0.999879,0.00002544266,0.00004181241,0.000009978188,0.00001890442,0.00002477608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004028396,0.00001964702,0.0004994232,0.0002114378,0.00000501362,0.0001593381,0.0000328014,0.0000189587,0.9951071,0.00005890451,0.00002119549,0.003463454],"study_design_scores_gemma":[0.00008033247,0.0009857059,0.02554162,0.00008344831,0.00009016007,0.001976874,0.0003261948,0.0004267681,0.9638409,0.0002668864,0.006369465,0.00001170525],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9052987,0.0851272,0.00591925,0.0004239657,0.00008499741,0.0001107185,0.0004767775,0.00005640404,0.002502032],"genre_scores_gemma":[0.9771641,0.01530359,0.003605901,0.0001060552,0.00005659502,0.0001448215,0.0004339758,0.000007567882,0.003177328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002064218,"threshold_uncertainty_score":0.006905556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02898734779401128,"score_gpt":0.2256071420805975,"score_spread":0.1966197942865862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}