{"id":"W1918246687","doi":"10.1002/ajmg.c.31362","title":"Molecular Mechanisms of Childhood Overgrowth","year":2013,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part C Seminars in Medical Genetics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; PTEN; Gene; Biology; Somatic cell; Cell biology; Genetics; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003127998,0.0004366735,0.0002878129,0.0005364983,0.0003155337,0.001035311,0.0005569662,0.0009971894,0.005529375],"category_scores_gemma":[0.0003449639,0.0001198222,0.0002536449,0.0002565701,0.0008264729,0.0006798066,0.0006195578,0.001323563,0.001150711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009471636,"about_ca_system_score_gemma":0.0005164613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003732981,"about_ca_topic_score_gemma":0.0004641128,"domain_scores_codex":[0.9998372,0.00002077601,0.00001013175,0.00002643091,0.00006267295,0.00004280773],"domain_scores_gemma":[0.99986,0.00003413415,0.0000338647,0.0000100019,0.00002381666,0.00003816272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004073248,0.0001369263,0.002420843,0.001465629,0.0001011264,0.003455001,0.0004264268,0.0009377516,0.08115098,0.1696252,0.3051394,0.4347335],"study_design_scores_gemma":[0.00004209499,0.0001181474,0.005218676,0.0002746124,0.00002970677,0.003444673,0.0001749898,0.0002520639,0.01526213,0.02210172,0.9530569,0.00002425766],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01865236,0.8486344,0.003970851,0.05975125,0.02524711,0.00005482602,0.0003535484,0.0003048234,0.04303079],"genre_scores_gemma":[0.1180065,0.7928548,0.002790764,0.009782922,0.01974032,0.0001044253,0.0004581386,0.00006539713,0.0561967],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005529375,"threshold_uncertainty_score":0.01849759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004497885081645766,"score_gpt":0.2488834564690859,"score_spread":0.2443855713874401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}