{"id":"W1918360240","doi":"10.1002/ijc.28781","title":"LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer","year":2014,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Goddard Space Flight Center; Fondation de France; Fondation ARC pour la Recherche sur le Cancer","keywords":"Breast cancer; Estrogen receptor; Biomarker; Cancer research; Subcellular localization; Cytoplasm; Cancer; Estrogen; Biology; Signal transduction; Internal medicine; Oncology; Medicine; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002025722,0.0001877557,0.0001906115,0.0009127689,0.0002061229,0.0003169212,0.000101207,0.0001900284,0.001363462],"category_scores_gemma":[0.0006394282,0.0001183694,0.0001125349,0.0006099705,0.0002070552,0.0001377392,0.0002111827,0.000171451,0.0002925001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002388701,"about_ca_system_score_gemma":0.0001277771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007105315,"about_ca_topic_score_gemma":0.001146271,"domain_scores_codex":[0.9998794,0.00002863478,0.00001359271,0.00002136419,0.00002667528,0.00003037136],"domain_scores_gemma":[0.9996437,0.0000453015,0.0001939272,0.0000171802,0.00003768977,0.00006224545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001399882,0.00001746442,0.935321,0.00007381989,0.00004784825,0.0008674241,0.0001187765,0.00009729731,0.05518518,0.00006018601,0.0002031629,0.00660801],"study_design_scores_gemma":[0.000008175243,0.0001112775,0.9884432,0.0000108848,0.00005166834,0.003651574,0.0001522887,0.0002797653,0.00639493,0.0001122341,0.0007787448,0.000005284589],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975605,0.001369838,0.0002405787,0.0000591319,0.000008562465,0.000004210397,0.0001410971,0.00001289129,0.0006031576],"genre_scores_gemma":[0.999204,0.0002477373,0.0001402142,0.000007779696,0.000007613421,0.000003377037,0.0001466425,0.000001954699,0.0002407313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001363462,"threshold_uncertainty_score":0.004561186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257825607649833,"score_gpt":0.3081078105965635,"score_spread":0.2955295545200652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}