{"id":"W1919831913","doi":"10.4049/jimmunol.1501132","title":"Not All SCID Pigs Are Created Equally: Two Independent Mutations in the <i>Artemis</i> Gene Cause SCID in Pigs","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institutes of Health; Iowa State University; University of Kansas","keywords":"Recombination-activating gene; Biology; Phenotype; RAG2; Gene; Mutation; Immune system; Severe combined immunodeficiency; Molecular biology; Genetics; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005709001,0.0005445877,0.0004347662,0.0008690759,0.0004338928,0.000605922,0.0004640557,0.001369098,0.002360023],"category_scores_gemma":[0.0005251952,0.0003055749,0.0005842455,0.0002687558,0.0009409438,0.0005467513,0.0007933503,0.0009715275,0.0007479806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002256531,"about_ca_system_score_gemma":0.000193623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001782004,"about_ca_topic_score_gemma":0.0003027182,"domain_scores_codex":[0.9994521,0.0001266536,0.00007386664,0.000136916,0.0001211224,0.00008930051],"domain_scores_gemma":[0.99939,0.0001364025,0.0001355874,0.0001698345,0.0000341248,0.0001340956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004519056,0.0002131435,0.00369682,0.0001223862,0.00007145829,0.002261737,0.0001314181,0.0001176213,0.9814139,0.001383863,0.0004734686,0.009662163],"study_design_scores_gemma":[0.0003109508,0.006686468,0.0800953,0.000201515,0.0003476256,0.05385266,0.0005138577,0.001929998,0.8164935,0.001883247,0.03757565,0.0001093234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791711,0.001826565,0.009199316,0.0007804074,0.0003259019,0.0001432683,0.0005819047,0.0003801302,0.007591376],"genre_scores_gemma":[0.9825829,0.001339666,0.006352286,0.0009631924,0.00007982972,0.0002002783,0.0007875898,0.0001422615,0.007551912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002360023,"threshold_uncertainty_score":0.007895052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04343941806015217,"score_gpt":0.2854111191787748,"score_spread":0.2419717011186226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}