{"id":"W1919886056","doi":"10.1002/mds.25395","title":"Long‐term safety and efficacy of preladenant in subjects with fluctuating Parkinson's disease","year":2013,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Dyskinesia; Medicine; Parkinson's disease; Adverse effect; Constipation; Clinical endpoint; Internal medicine; Levodopa; Central nervous system disease; Anesthesia; Randomized controlled trial; Disease; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009883567,0.000302691,0.0006601357,0.0001648435,0.0003224676,0.0002753508,0.0002095114,0.0002762904,0.000973978],"category_scores_gemma":[0.001020022,0.0001288808,0.0002532162,0.0001700226,0.000218333,0.000241879,0.0001395406,0.0004813429,0.0002360613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222979,"about_ca_system_score_gemma":0.0002317671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000416305,"about_ca_topic_score_gemma":0.0008057377,"domain_scores_codex":[0.9997749,0.00007777867,0.00002797253,0.00004194356,0.00004840375,0.00002897714],"domain_scores_gemma":[0.9993297,0.0001418696,0.0002748774,0.00004389611,0.00008288035,0.000126863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3108526,0.01224623,0.2042307,0.001182839,0.001201823,0.00124297,0.0008719843,0.001264577,0.1273615,0.00009406103,0.001226315,0.3382244],"study_design_scores_gemma":[0.02365558,0.3286155,0.6263708,0.00009176958,0.0009060741,0.002188085,0.00030946,0.001233203,0.01415428,0.0001424895,0.002289632,0.00004316876],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982827,0.001128253,0.0001150762,0.00002429225,0.000007111914,0.00004963224,0.0001143989,0.00001564853,0.0002630187],"genre_scores_gemma":[0.9989814,0.0002981534,0.0002134007,0.00006277937,0.00001929446,0.0000430182,0.0002073377,0.000002618388,0.0001719234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009883567,"threshold_uncertainty_score":0.00522697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004187359533840365,"score_gpt":0.2090643607666814,"score_spread":0.204877001232841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}