{"id":"W1920246049","doi":"10.1016/j.psyneuen.2015.10.001","title":"Structural &amp; functional consequences of chronic psychosocial stress on the microbiome &amp; host","year":2015,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":293,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Office of Naval Research; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation; McMaster University","keywords":"Microbiome; Biology; Metagenomics; Chronic stress; Social defeat; Phenotype; Immune system; Genetics; Immunology; Psychology; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002362734,0.0002701274,0.0003097163,0.0001912859,0.0003383321,0.0007568979,0.0001281545,0.0004276655,0.002624583],"category_scores_gemma":[0.0004110779,0.0001131351,0.0001560076,0.000179367,0.0005378695,0.0002952925,0.000651869,0.000586067,0.0001930798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002475024,"about_ca_system_score_gemma":0.0002431547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004134921,"about_ca_topic_score_gemma":0.0005691444,"domain_scores_codex":[0.9998509,0.00004936326,0.000006483937,0.00002824951,0.0000263388,0.0000387063],"domain_scores_gemma":[0.999783,0.00003686395,0.00006269065,0.00001680599,0.00001889675,0.0000816832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00534111,0.0003333187,0.0653654,0.001228132,0.0002444806,0.001717584,0.0008581289,0.001095054,0.8115481,0.006981724,0.001736323,0.1035507],"study_design_scores_gemma":[0.0001096616,0.002224779,0.9050883,0.0003137361,0.0001550003,0.002578731,0.002153571,0.001830148,0.060065,0.01035908,0.01505201,0.00006995233],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9663472,0.02226606,0.002334042,0.001690518,0.0002291917,0.00002543373,0.001012534,0.00003772749,0.006057196],"genre_scores_gemma":[0.9929498,0.004554725,0.0007639865,0.0001777273,0.0000691102,0.0000285004,0.0001439175,0.00000584484,0.001306342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002624583,"threshold_uncertainty_score":0.008780062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05612634835587111,"score_gpt":0.3104452640646057,"score_spread":0.2543189157087345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}