{"id":"W1921220968","doi":"10.1139/bcb-2014-0067","title":"Inhibitory effects of kaempferol on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"China Postdoctoral Science Foundation; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Kaempferol; Cancer research; MAPK/ERK pathway; Matrix metalloproteinase; Protein kinase C; Metastasis; Chemistry; Signal transduction; Biology; Molecular biology; Cell biology; Cancer; Biochemistry; Flavonoid","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001121476,0.0003654372,0.000280715,0.0002530893,0.0001312618,0.0001479585,0.0001002883,0.0001909409,0.0008570828],"category_scores_gemma":[0.0001100051,0.0001032638,0.0002357806,0.0001250284,0.0001417114,0.0001796989,0.0001204098,0.0005053222,0.0002006991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001137417,"about_ca_system_score_gemma":0.0001401892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005569307,"about_ca_topic_score_gemma":0.0006721856,"domain_scores_codex":[0.999927,0.00001472006,0.000007078702,0.000009818979,0.00001677074,0.00002454503],"domain_scores_gemma":[0.9999561,0.00001340369,0.000007824951,0.000005401567,0.000007388201,0.000009863226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004177232,0.0002114206,0.0001754161,0.0001133327,0.00001024058,0.00006458154,0.00003431002,0.00008554906,0.9948655,0.00004236496,0.00008574639,0.00389395],"study_design_scores_gemma":[0.0001000154,0.001952802,0.006276829,0.00002692576,0.00005763802,0.000288437,0.00005944304,0.001023035,0.9867991,0.00007150192,0.003334176,0.00001018396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914331,0.005877598,0.0009463753,0.0001347345,0.00003981399,0.00003797096,0.0001568658,0.00004168108,0.001331784],"genre_scores_gemma":[0.9930404,0.004290073,0.0008654107,0.00009307351,0.00002223424,0.0000343903,0.0002708114,0.000005596465,0.001377928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008570828,"threshold_uncertainty_score":0.002867222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004460395389920865,"score_gpt":0.2019169203736555,"score_spread":0.1974565249837347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}