{"id":"W1921553292","doi":"10.1099/vir.0.000141","title":"Downregulation of viral RNA translation by hepatitis C virus non-structural protein NS5A requires the poly(U/UC) sequence in the 3′ UTR","year":2015,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"NS5A; Virology; Five prime untranslated region; Biology; RNA; Untranslated region; Translation (biology); Hepatitis C virus; Molecular biology; Virus; Messenger RNA; Hepacivirus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001466536,0.0001482024,0.0003870253,0.0001936851,0.0000646366,0.00002158541,0.0003338699,0.0001622468,0.00005900423],"category_scores_gemma":[0.000224019,0.00008283002,0.000122921,0.000218484,0.0003057354,0.0002651387,0.00002718471,0.00056938,0.000004843402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001393835,"about_ca_system_score_gemma":0.0002938472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00318598,"about_ca_topic_score_gemma":0.001024634,"domain_scores_codex":[0.9973425,0.0006735675,0.0007726258,0.0001446499,0.0007634069,0.0003032699],"domain_scores_gemma":[0.9988624,0.0001002934,0.0004135542,0.0002604401,0.0002476964,0.0001156098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009116475,0.00005461197,0.01872424,0.00001936096,0.00004875264,0.00009288917,0.001455242,0.0001854084,0.9457731,0.0002493061,0.00132753,0.03115791],"study_design_scores_gemma":[0.01074897,0.009025361,0.6794194,0.0002093089,0.0002137412,0.0014012,0.0002631437,0.03102203,0.2491831,0.007164618,0.01088046,0.0004686185],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893946,0.000895727,0.00043724,0.008118349,0.0001256825,0.0004955432,0.00002245903,0.000004462234,0.0005059521],"genre_scores_gemma":[0.997555,0.0001591096,0.00115273,0.0005789508,0.0004090959,0.00001584861,0.00001493397,0.00001576519,0.00009852849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6965899,"threshold_uncertainty_score":0.4816271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06161363810892188,"score_gpt":0.3495998692592525,"score_spread":0.2879862311503306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}