{"id":"W1921751791","doi":"10.1111/bjh.13596","title":"Therapeutic targeting of N‐cadherin is an effective treatment for multiple myeloma","year":2015,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Royal Adelaide Hospital; Cancer Australia; Leukaemia Foundation; Multiple Myeloma Research Foundation","keywords":"Cadherin; Stromal cell; Bone marrow; Medicine; Multiple myeloma; Extravasation; Small hairpin RNA; Homing (biology); Cancer research; Pathogenesis; Pathology; Internal medicine; Cell culture; Cell; Chemistry; Biology; Gene knockdown","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039163,0.0001391186,0.0007964462,0.0001283809,0.00005490982,0.0000151392,0.0001009286,0.0001041512,0.00004209077],"category_scores_gemma":[0.0005083019,0.000118972,0.0002276997,0.0000853601,0.0001083281,0.0001167513,0.00001832606,0.0001297228,0.000005964752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001387933,"about_ca_system_score_gemma":0.0002062341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002344212,"about_ca_topic_score_gemma":0.00007281108,"domain_scores_codex":[0.9985759,0.0001834092,0.0004986362,0.0001683014,0.0002540713,0.0003196754],"domain_scores_gemma":[0.9982867,0.0002964734,0.0003111895,0.000129514,0.0006152745,0.0003608705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.01070639,0.004384464,0.1914496,0.0004494833,0.003255086,0.03394486,0.002785384,0.00002131415,0.01287976,0.0001304389,0.003095844,0.7368973],"study_design_scores_gemma":[0.1122193,0.05598238,0.203326,0.001377958,0.001330692,0.3420584,0.004166853,0.004160686,0.2585001,0.002912056,0.01329944,0.0006661438],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923553,0.005484213,0.0008076559,0.0002663327,0.0001444462,0.0007761265,0.00004040787,0.00001085628,0.000114679],"genre_scores_gemma":[0.993711,0.0001987276,0.005715588,0.00007656818,0.0001217996,0.00004812399,0.00001913199,0.0000265077,0.00008255351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7362312,"threshold_uncertainty_score":0.4851536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0663614294524306,"score_gpt":0.3575109046384235,"score_spread":0.2911494751859929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}