{"id":"W192250670","doi":"10.4049/jimmunol.182.supp.35.8","title":"Ran overexpression leads to a compromised transcription factor nuclear translocation and diminished T-cells response to TCR activation (35.8)","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Interdisciplinary Research in Rehabilitation","funders":"","keywords":"NFAT; Ran; Biology; Cell biology; Nuclear protein; Activator (genetics); Molecular biology; T cell; Transcription factor; Immune system; Receptor; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001537659,0.0006201994,0.0002630401,0.0002812843,0.0001930244,0.0004847715,0.0002550468,0.0003940225,0.002825817],"category_scores_gemma":[0.0001143044,0.0002627857,0.0003023398,0.0001668889,0.0003881599,0.0001984213,0.0002868363,0.0008698116,0.001181846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002940432,"about_ca_system_score_gemma":0.0001380118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003393126,"about_ca_topic_score_gemma":0.0004605374,"domain_scores_codex":[0.9997171,0.00005112915,0.00003671812,0.0000707861,0.00005581184,0.00006848494],"domain_scores_gemma":[0.9997618,0.00003790754,0.00007351889,0.00003399409,0.00001544406,0.00007727784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005014895,0.000007641579,0.00001986306,0.000008745962,0.000001009982,0.0000473568,0.000004539665,0.00001094616,0.9997215,0.0000307793,0.00000634744,0.00009113614],"study_design_scores_gemma":[0.00001381422,0.0001383329,0.001546236,0.000004546445,0.00001259919,0.0003248844,0.00002385063,0.0003581668,0.9962245,0.00003255368,0.00131662,0.000003996741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944925,0.0007599813,0.002719144,0.00007354231,0.00004375501,0.00001878435,0.000504045,0.0001678714,0.001220434],"genre_scores_gemma":[0.9903829,0.0004473928,0.002242743,0.00004331417,0.00001456258,0.0000391158,0.0008314323,0.00009192507,0.005906794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002825817,"threshold_uncertainty_score":0.009453356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008277170463400268,"score_gpt":0.2279481656297901,"score_spread":0.2196709951663899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}