{"id":"W1922670199","doi":"10.4049/jimmunol.1301271","title":"Calcineurin–Rcan1 Interaction Contributes to Stem Cell Factor–Mediated Mast Cell Activation","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"NFAT; Calcineurin; Stem cell factor; Cell biology; Transcription factor; Stem cell; Progenitor cell; Signal transduction; Biology; Mast cell; Haematopoiesis; Chemistry; Transplantation; Immunology; Internal medicine; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738589,0.0001239969,0.0001562496,0.00007397235,0.00005943382,0.00002019607,0.0003212889,0.0001167967,0.00008395346],"category_scores_gemma":[0.0001001228,0.00008715842,0.00007502867,0.00008908254,0.00005154038,0.00001136506,0.00009430084,0.0002228852,0.00007647969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004683105,"about_ca_system_score_gemma":0.000075519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003374584,"about_ca_topic_score_gemma":0.00000200589,"domain_scores_codex":[0.9990705,0.0002120296,0.0003316645,0.0001016371,0.00009275601,0.0001914529],"domain_scores_gemma":[0.998934,0.0001114672,0.0003372185,0.0002436556,0.0003136018,0.00006001692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003696102,0.00007588735,0.0006290052,0.000005869254,0.00006855857,0.00000140198,0.0001180991,0.0001850356,0.9944899,0.00000198072,0.003122475,0.0009321759],"study_design_scores_gemma":[0.0007188901,0.0005472286,0.007019446,0.00001721746,0.00002637379,0.00002787744,0.0004578275,0.00001460513,0.9859783,0.00002361508,0.005081841,0.00008677577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954621,0.0007126507,0.002158388,0.0008192498,0.0005011141,0.0001814404,0.000008165533,0.000006250224,0.0001506536],"genre_scores_gemma":[0.9989034,0.0000841285,0.00004518807,0.0004866474,0.0001359176,0.000006597646,0.00001136445,0.0000168888,0.0003098906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008511599,"threshold_uncertainty_score":0.3554217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079040316933723,"score_gpt":0.2303602342518022,"score_spread":0.2195698310824649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}