{"id":"W1922821260","doi":"10.1186/s13148-015-0114-0","title":"DNA methylation signature of interleukin 1 receptor type II in asthma","year":2015,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Université du Québec à Chicoutimi","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"DNA methylation; Interleukin 1 receptor, type II; Interleukin 1 receptor, type I; Methylation; Promoter; Gene; Biology; Epigenetics; Genetics; Molecular biology; Immunology; Gene expression; Interleukin; Interleukin 5; Interleukin-21 receptor; Cytokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009821969,0.0001365775,0.0004052209,0.00007814752,0.000036631,0.000003440582,0.0002297723,0.0006783367,0.0001609718],"category_scores_gemma":[0.002127307,0.0001216034,0.00009444232,0.0002364086,0.0002421489,0.00003343779,0.0001028029,0.0005173316,0.0002987682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002919468,"about_ca_system_score_gemma":0.0002133168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001903089,"about_ca_topic_score_gemma":0.00004635557,"domain_scores_codex":[0.9982473,0.0004321837,0.0007698512,0.0002660117,0.00004620649,0.0002384774],"domain_scores_gemma":[0.9988646,0.0003370617,0.0002084148,0.0002982777,0.0002437035,0.00004793025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002652173,0.002764715,0.04657945,0.0001127715,0.0004226925,0.00001329771,0.007084363,0.0002837983,0.6380045,0.004183304,0.06568964,0.2322092],"study_design_scores_gemma":[0.00452134,0.005265889,0.05225711,0.0001253466,0.00005156316,0.000005793187,0.0005750344,0.00004987792,0.2538407,0.003831775,0.6789845,0.0004909907],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990851,0.00214336,0.0001904025,0.0001191101,0.00302799,0.0001642613,0.0001804463,0.00002884193,0.003294573],"genre_scores_gemma":[0.9973815,0.0003720906,0.0007937592,0.0001662145,0.0001180618,0.000002986309,0.0001370697,0.00001332113,0.001014983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6132949,"threshold_uncertainty_score":0.5231954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07982480183943977,"score_gpt":0.3463216062896488,"score_spread":0.266496804450209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}