{"id":"W1922821260","doi":"10.1186/s13148-015-0114-0","title":"DNA methylation signature of interleukin 1 receptor type II in asthma","year":2015,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Université du Québec à Chicoutimi","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"DNA methylation; Interleukin 1 receptor, type II; Interleukin 1 receptor, type I; Methylation; Promoter; Gene; Biology; Epigenetics; Genetics; Molecular biology; Immunology; Gene expression; Interleukin; Interleukin 5; Interleukin-21 receptor; Cytokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001240779,0.0001112361,0.0001614454,0.0003631176,0.000097859,0.0001598823,0.00008791778,0.0001508455,0.001814308],"category_scores_gemma":[0.0002894579,0.00008891772,0.00009374652,0.0002047986,0.0001138945,0.00005444356,0.0001127705,0.0001619267,0.0002282328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009498706,"about_ca_system_score_gemma":0.00008168102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007439655,"about_ca_topic_score_gemma":0.001359544,"domain_scores_codex":[0.9999005,0.00002770415,0.000005535764,0.00003125165,0.00001824134,0.00001683243],"domain_scores_gemma":[0.9998857,0.00002646614,0.00004892769,0.000008812063,0.00001618929,0.0000139869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007513756,0.00003303194,0.1202252,0.0001184498,0.0001101564,0.0002847679,0.0002640682,0.0001295897,0.859899,0.0001868272,0.00025944,0.01773803],"study_design_scores_gemma":[0.00001859047,0.0002307876,0.9417418,0.00002042773,0.00009673087,0.001396246,0.0001459069,0.000548752,0.05358816,0.0003187578,0.001883204,0.00001063936],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946789,0.002563186,0.001047735,0.00007824802,0.00001092862,0.00001117274,0.0004752853,0.00002150723,0.00111317],"genre_scores_gemma":[0.9983419,0.0004029697,0.000316788,0.00003251584,0.00000689158,0.000009576684,0.0002242557,0.000004314916,0.0006606986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001814308,"threshold_uncertainty_score":0.006069481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07982480183943977,"score_gpt":0.3463216062896488,"score_spread":0.266496804450209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}