{"id":"W1923559986","doi":"10.3109/08916934.2015.1077233","title":"Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution","year":2015,"lang":"en","type":"article","venue":"Autoimmunity","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Center for Research Resources; U.S. Public Health Service","keywords":"Epitope; Autoantibody; Epitope mapping; Ribonucleoprotein; Molecular biology; Antibody; Peptide; Amino acid; Biology; Immunology; RNA; Chemistry; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008620403,0.0002580394,0.0002061571,0.0002068246,0.0001065975,0.0002659682,0.0001288777,0.000311171,0.0005929922],"category_scores_gemma":[0.0001905079,0.0001630624,0.0001657326,0.0001860126,0.0001156545,0.0001854901,0.0001498534,0.0002235058,0.0003401061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001842706,"about_ca_system_score_gemma":0.00009851713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003672419,"about_ca_topic_score_gemma":0.0005881944,"domain_scores_codex":[0.9999199,0.00001229461,0.000004206388,0.00002216398,0.00002171389,0.00001980458],"domain_scores_gemma":[0.9998989,0.00003377078,0.00003096729,0.00000833196,0.00001222132,0.00001571323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004458227,0.000005516498,0.0008482316,0.00002005383,0.000004244706,0.00003041232,0.00001379504,0.0001294643,0.9978022,0.00001746067,0.00002226546,0.001061722],"study_design_scores_gemma":[0.00002431199,0.0006573722,0.09068628,0.00002519998,0.00005206654,0.001644525,0.0001762074,0.008564183,0.8949076,0.0003441364,0.002897112,0.00002091608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995229,0.0008118898,0.002944469,0.00003256401,0.000005964275,0.00001022651,0.0002298317,0.0000347504,0.0007013269],"genre_scores_gemma":[0.9921644,0.0004519479,0.006559472,0.00005343526,0.000006069737,0.00002197302,0.0003702894,0.000008312289,0.0003641639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005929922,"threshold_uncertainty_score":0.001983821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1200437218938578,"score_gpt":0.323155475239075,"score_spread":0.2031117533452172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}