{"id":"W1924202047","doi":"10.1111/j.1758-2229.2010.00222.x","title":"A two‐tier model of polymyxin B resistance in <i>Burkholderia cenocepacia</i>","year":2010,"lang":"en","type":"article","venue":"Environmental Microbiology Reports","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Western University","funders":"","keywords":"Bacterial outer membrane; Burkholderia cenocepacia; Microbiology; Polymyxin B; Polymyxin; Lipopolysaccharide; Biology; Burkholderia; Antibiotic resistance; Bacteria; Antibiotics; Gene; Escherichia coli; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003295018,0.0005205515,0.0005058137,0.0004995936,0.0003562823,0.001038484,0.0008263824,0.000935594,0.002215986],"category_scores_gemma":[0.0004702169,0.0003114348,0.0006924467,0.0002930081,0.0005150182,0.001073003,0.0004995184,0.0005519988,0.0005904315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001039647,"about_ca_system_score_gemma":0.0005719886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003568674,"about_ca_topic_score_gemma":0.002436366,"domain_scores_codex":[0.9996343,0.00006902255,0.00002450393,0.00009123802,0.0000730956,0.0001078809],"domain_scores_gemma":[0.9996514,0.00008248904,0.00009674962,0.00004161789,0.00004483509,0.00008289234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008201004,0.0004940794,0.01230031,0.0003401855,0.0001047949,0.001049277,0.0002259149,0.03190228,0.9035068,0.03830467,0.001603694,0.009347972],"study_design_scores_gemma":[0.0003836317,0.002599928,0.04865464,0.00008786262,0.0001585157,0.003206602,0.0005036947,0.7003738,0.1725232,0.0604,0.01088433,0.0002238933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9455059,0.001575927,0.0433952,0.001474725,0.0000622348,0.000157432,0.0004814729,0.0004990319,0.006848095],"genre_scores_gemma":[0.9903247,0.0003721338,0.006397453,0.0002441202,0.000009060992,0.00005652976,0.0002180557,0.00001540746,0.002362534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003568674,"threshold_uncertainty_score":0.007543266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006173678423166891,"score_gpt":0.2452497984424792,"score_spread":0.2390761200193123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}