{"id":"W1926700313","doi":"10.1111/j.1432-1033.2003.03976.x","title":"The zinc‐binding site of a class I aminoacyl‐tRNA synthetase is a SWIM domain that modulates amino acid binding via the tRNA acceptor arm","year":2004,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"","keywords":"Transfer RNA; Amino Acyl-tRNA Synthetases; Escherichia coli; Binding site; Biochemistry; Amino acid; Biology; Zinc finger; Binding domain; Active site; Stereochemistry; Enzyme; Chemistry; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001774917,0.0003658438,0.0003371443,0.00005887056,0.0003970978,0.0001351422,0.001068854,0.0001295421,0.00005118114],"category_scores_gemma":[0.0002109808,0.0002297449,0.000483302,0.0001511826,0.0002979663,0.00001801949,0.0002735176,0.0003610985,0.00003427829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005640594,"about_ca_system_score_gemma":0.0001160641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000290163,"about_ca_topic_score_gemma":9.16292e-7,"domain_scores_codex":[0.9976398,0.0003266485,0.0007507981,0.0003602333,0.0004678725,0.0004546944],"domain_scores_gemma":[0.9977349,0.00007502708,0.001095714,0.0007453112,0.0001553995,0.0001936534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002028109,0.00008754958,0.0001579401,0.0000374747,0.0002361457,0.00007368644,0.0002339375,0.00002146309,0.9933561,0.00001055297,0.0004376387,0.005144686],"study_design_scores_gemma":[0.0008474857,0.0003114785,0.0001787729,0.000186946,0.00008226123,0.0004596472,0.0005706507,0.000004073014,0.9900687,0.00009934845,0.006918749,0.0002718504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923828,0.003014161,0.00227573,0.0008314171,0.0002645729,0.000166055,0.00006588449,0.000009475169,0.0009899321],"genre_scores_gemma":[0.996832,0.0006465818,0.001333099,0.0001676704,0.0005790359,0.00000402828,0.0000180677,0.00007045592,0.0003490856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00648111,"threshold_uncertainty_score":0.9368726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146300001964961,"score_gpt":0.2192176777927266,"score_spread":0.207754677773077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}