{"id":"W1927036751","doi":"10.1016/j.taap.2015.10.003","title":"19-Hydroxyeicosatetraenoic acid and isoniazid protect against angiotensin II-induced cardiac hypertrophy","year":2015,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Muscle hypertrophy; Endocrinology; Angiotensin II; In vivo; Chemistry; Metabolite; Arachidonic acid; Medicine; Biology; Biochemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003366229,0.001005697,0.001009049,0.0006654971,0.00042998,0.0004564101,0.0008002876,0.0006393571,0.003319723],"category_scores_gemma":[0.0003389794,0.0004422149,0.0006093026,0.0003427249,0.0008388038,0.0007869019,0.0004300921,0.002180449,0.0007054469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003395568,"about_ca_system_score_gemma":0.000855747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001249971,"about_ca_topic_score_gemma":0.001861126,"domain_scores_codex":[0.9997781,0.0000400325,0.0000255731,0.00002746556,0.00003250422,0.00009627405],"domain_scores_gemma":[0.9995098,0.00004032573,0.00009074172,0.00007196534,0.00003462801,0.0002524423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03448678,0.003050498,0.0008274145,0.0001964943,0.0001337527,0.000479683,0.0001016464,0.0003039351,0.9493936,0.0004779072,0.0003224664,0.01022581],"study_design_scores_gemma":[0.002603811,0.01170295,0.01052403,0.00003058098,0.0002142638,0.0003168275,0.0002437939,0.0009698684,0.9708426,0.0003201943,0.002199879,0.00003133564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933287,0.002326392,0.001507635,0.0003436473,0.0002868625,0.0000875322,0.0003236803,0.0001672391,0.001628299],"genre_scores_gemma":[0.9893352,0.002320015,0.001346124,0.0002137553,0.0001724426,0.00009099781,0.0005424672,0.0000398889,0.005939074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003319723,"threshold_uncertainty_score":0.01110554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02198347499146577,"score_gpt":0.271343804725835,"score_spread":0.2493603297343693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}