{"id":"W192708085","doi":"10.1152/jappl.2001.91.2.693","title":"Insight into skeletal muscle mechanotransduction: MAPK activation is quantitatively related to tension","year":2001,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":257,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Mechanotransduction; MAPK/ERK pathway; Isometric exercise; Kinase; Cell biology; Phosphorylation; Skeletal muscle; Muscle contraction; p38 mitogen-activated protein kinases; Chemistry; Extracellular; Signal transduction; Contraction (grammar); Biology; Biophysics; Internal medicine; Anatomy; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000556148,0.0008113388,0.0004381895,0.0005744231,0.0001210667,0.0004806105,0.0007271636,0.0004902266,0.002474407],"category_scores_gemma":[0.0007963106,0.0003205482,0.0003819276,0.0005110477,0.0004606582,0.001500626,0.0004227369,0.0009118401,0.0007330928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003802577,"about_ca_system_score_gemma":0.0001695425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004274238,"about_ca_topic_score_gemma":0.0004369483,"domain_scores_codex":[0.9997306,0.00003902126,0.00002104782,0.000097344,0.00008351865,0.00002828491],"domain_scores_gemma":[0.9997568,0.00009312625,0.00007240876,0.00002856818,0.00002986007,0.00001917878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001129213,0.00004441207,0.00171646,0.0002997368,0.00001875575,0.00005535919,0.00003096952,0.0006829067,0.9857632,0.001020885,0.00008859434,0.01016581],"study_design_scores_gemma":[0.00004746021,0.001275743,0.1875172,0.0001192735,0.0001398133,0.001991184,0.0001997517,0.06168376,0.7283832,0.0114739,0.007081764,0.00008689972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7858842,0.02251501,0.1799657,0.001337087,0.0002090214,0.0001008485,0.001373287,0.0007415859,0.007873356],"genre_scores_gemma":[0.9630939,0.009830141,0.02331713,0.0002907451,0.0001129272,0.0001069883,0.0004795319,0.000102201,0.002666329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002474407,"threshold_uncertainty_score":0.008277655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01067631416105955,"score_gpt":0.2566807414207162,"score_spread":0.2460044272596567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}