{"id":"W192747251","doi":"10.1054/bjoc.2001.2170","title":"Internalisation enhances photo-induced cytotoxicity of monoclonal antibody-phthalocyanine conjugates","year":2001,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Conjugate; Cytotoxicity; Monoclonal antibody; Molecular biology; Carcinoembryonic antigen; Chemistry; Cell culture; Antigen; Incubation; Antibody; Monoclonal; Biology; Biochemistry; In vitro; Medicine; Immunology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004537643,0.0001244894,0.0005405508,0.0001356829,0.00005719347,0.00002852692,0.0001695182,0.00005934636,0.0008665242],"category_scores_gemma":[0.0002273657,0.0001193209,0.0001846982,0.0002028491,0.0001495797,0.0002154976,0.00003668838,0.0003508403,0.000001702711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000161912,"about_ca_system_score_gemma":0.0002426779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00211176,"about_ca_topic_score_gemma":0.0005833718,"domain_scores_codex":[0.9983276,0.00006852208,0.0006016038,0.0001362276,0.0006238688,0.0002421928],"domain_scores_gemma":[0.9984528,0.00008402367,0.0004803702,0.00009618707,0.0007476618,0.0001389486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001215567,0.0001819563,0.02089597,0.00006142394,0.0004732339,0.0007269838,0.0001729799,0.000007064136,0.9577754,0.000004697918,0.0002810001,0.01820378],"study_design_scores_gemma":[0.003413766,0.001008445,0.2576559,0.00215626,0.0001013314,0.005400969,0.0002122809,0.0001634964,0.728384,0.000200769,0.001155365,0.0001473804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892711,0.008998356,0.0001478107,0.000345582,0.0002327951,0.0002119423,0.0000318492,0.00001004057,0.0007505254],"genre_scores_gemma":[0.9771399,0.02185777,0.0001600535,0.0001527459,0.000400117,0.000008950642,0.00000422278,0.00001779604,0.0002584029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.23676,"threshold_uncertainty_score":0.9487833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649090783885711,"score_gpt":0.3661352975555311,"score_spread":0.339644389716674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}