{"id":"W1927992572","doi":"10.4049/jimmunol.1003615","title":"CD1d and CD1c Expression in Human B Cells Is Regulated by Activation and Retinoic Acid Receptor Signaling","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"B.C. Women's Hospital & Health Centre; BC Children's Hospital; Children's & Women's Health Centre of British Columbia; Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"CD1D; CD40; Cell biology; Downregulation and upregulation; Biology; Natural killer T cell; Retinoic acid; T cell; Molecular biology; Immunology; Immune system; Cytotoxic T cell; Cell culture; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001747748,0.0001948256,0.0002065796,0.0006940716,0.0002889278,0.000601252,0.0001078029,0.0002807835,0.002018668],"category_scores_gemma":[0.0002669559,0.0001709812,0.0001402654,0.0005277005,0.0002184906,0.0001415839,0.0002258302,0.0003333833,0.000678633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005706,"about_ca_system_score_gemma":0.0001910866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001404209,"about_ca_topic_score_gemma":0.0009158223,"domain_scores_codex":[0.99965,0.00006052633,0.00002695478,0.00009246695,0.00009764296,0.00007252854],"domain_scores_gemma":[0.9998703,0.00002525699,0.00003687631,0.00001465011,0.00003072156,0.0000222139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002103091,0.00001287462,0.001562822,0.00003836008,0.000005705889,0.00003533967,0.00004417045,0.00003478574,0.9948644,0.00005499708,0.00008077951,0.00305557],"study_design_scores_gemma":[0.000037297,0.000174025,0.09127169,0.00002420375,0.00002882187,0.000873993,0.0001396695,0.0007192476,0.8953283,0.0000989558,0.01128835,0.00001542724],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870674,0.008823729,0.001079435,0.0001331365,0.00001492103,0.00002053578,0.0006674683,0.00005564684,0.002137693],"genre_scores_gemma":[0.9932626,0.002103353,0.001443064,0.00006681682,0.00001013588,0.00005092336,0.000985703,0.00001483155,0.00206246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002018668,"threshold_uncertainty_score":0.006753087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353038663490614,"score_gpt":0.2160641151799465,"score_spread":0.2025337285450404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}