{"id":"W1928008970","doi":"10.4049/jimmunol.169.10.5571","title":"Human MHC Class I Transgenic Mice Deficient for H2 Class I Expression Facilitate Identification and Characterization of New HLA Class I-Restricted Viral T Cell Epitopes","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Toronto Rehabilitation Institute; University of Toronto","funders":"","keywords":"Epitope; CTL*; Human leukocyte antigen; Biology; MHC class I; CD8; Beta-2 microglobulin; Major histocompatibility complex; T cell; Virology; Cytotoxic T cell; Molecular biology; Immunology; Antigen; Genetics; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006145268,0.0002422604,0.000507757,0.0002939861,0.0003644643,0.00002464413,0.0005065882,0.0003432898,0.0001612054],"category_scores_gemma":[0.00007958733,0.0001757217,0.0001972653,0.0001720286,0.0004153423,0.000251135,0.0000508638,0.0004571123,0.00002561974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005063656,"about_ca_system_score_gemma":0.00006129808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003593624,"about_ca_topic_score_gemma":0.000002628956,"domain_scores_codex":[0.9973903,0.0008858555,0.001109133,0.0001851533,0.00007232084,0.0003571859],"domain_scores_gemma":[0.9979017,0.0003608011,0.001128377,0.0003433602,0.0002448273,0.00002090305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002068111,0.0002322641,0.00003330973,0.0000307673,0.0002324782,4.956563e-7,0.003584479,0.00001402817,0.9861875,0.0001174372,0.0006949636,0.006804226],"study_design_scores_gemma":[0.004091104,0.001542798,0.01285316,0.00007713895,0.0001779139,0.000162346,0.0007115524,0.00002347844,0.9457846,0.0001220842,0.0342652,0.0001885822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771751,0.01816103,0.002447104,0.0008207315,0.0008899115,0.0004046191,0.00004496008,0.00001820113,0.00003838152],"genre_scores_gemma":[0.9913507,0.003688645,0.00004204528,0.00007539463,0.00004385914,0.000008909223,0.00004447039,0.00002446574,0.004721498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04040279,"threshold_uncertainty_score":0.7165721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02339189464580398,"score_gpt":0.2387819445611535,"score_spread":0.2153900499153495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}