{"id":"W1928008970","doi":"10.4049/jimmunol.169.10.5571","title":"Human MHC Class I Transgenic Mice Deficient for H2 Class I Expression Facilitate Identification and Characterization of New HLA Class I-Restricted Viral T Cell Epitopes","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Toronto Rehabilitation Institute; University of Toronto","funders":"","keywords":"Epitope; CTL*; Human leukocyte antigen; Biology; MHC class I; CD8; Beta-2 microglobulin; Major histocompatibility complex; T cell; Virology; Cytotoxic T cell; Molecular biology; Immunology; Antigen; Genetics; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001732379,0.0004595352,0.0002363212,0.0003579313,0.00011773,0.0003179947,0.0002064721,0.0003399411,0.003778451],"category_scores_gemma":[0.00006964659,0.0002414399,0.0001773659,0.0002240544,0.0001737259,0.0002554383,0.0002203261,0.0006559848,0.001332044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001499928,"about_ca_system_score_gemma":0.0001351031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002071344,"about_ca_topic_score_gemma":0.0003524736,"domain_scores_codex":[0.9998888,0.00001327215,0.0000112594,0.00003647602,0.00002410674,0.00002612234],"domain_scores_gemma":[0.9999161,0.00001137813,0.00002706773,0.00001259984,0.00000523774,0.00002760091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352382,0.00003169599,0.0001940216,0.0000234642,0.000003948256,0.00004889366,0.00001189143,0.00002867342,0.997995,0.000169226,0.0001153614,0.001242665],"study_design_scores_gemma":[0.00009683187,0.0005017843,0.003864952,0.00001802579,0.00003666095,0.0009362315,0.00002879009,0.0007801371,0.979536,0.0001655512,0.01402702,0.000008050018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9556603,0.002039853,0.0325415,0.0002037993,0.00009875224,0.0002216294,0.003382647,0.0008720587,0.004979509],"genre_scores_gemma":[0.9559625,0.002633765,0.02134601,0.0001632408,0.00005632781,0.0002806264,0.004116559,0.000197416,0.01524362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003778451,"threshold_uncertainty_score":0.01264018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02339189464580398,"score_gpt":0.2387819445611535,"score_spread":0.2153900499153495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}