{"id":"W1928310179","doi":"10.1093/nar/gkv825","title":"The histone variant H2A.Z is an important regulator of enhancer activity","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Enhancer; Enhancer RNAs; Biology; Chromatin; RNA polymerase II; Promoter; Histone; Chromatin immunoprecipitation; Transcription (linguistics); Regulation of gene expression; Genetics; Cell biology; Molecular biology; Gene; Transcription factor; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001626255,0.0001086165,0.0001341385,0.0000373902,0.0001825293,0.00003943469,0.0004956446,0.0001534365,0.00003484698],"category_scores_gemma":[0.0001646791,0.00008096184,0.00006128212,0.0001363442,0.0003262031,0.000005539477,0.0003001193,0.0001939886,0.00001251627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007175162,"about_ca_system_score_gemma":0.0003729174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001248316,"about_ca_topic_score_gemma":0.00009797336,"domain_scores_codex":[0.9984766,0.0001592083,0.0002207601,0.0003147702,0.0004564166,0.0003722623],"domain_scores_gemma":[0.9984367,0.00002072093,0.00009004521,0.0008705325,0.0003941513,0.000187842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002178897,0.0001322485,0.0006567159,0.00001253116,0.0000483625,0.000004902586,0.0003707926,0.000007701118,0.9844022,0.0006679832,0.007399883,0.006078751],"study_design_scores_gemma":[0.001185829,0.001938503,0.0112639,0.00001730314,0.00001795191,0.00004076126,0.0008760602,0.006635144,0.8382259,0.00320447,0.1362177,0.0003765108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966248,0.0005328823,0.0001529108,0.0004377255,0.0001030448,0.0001737354,0.0000279407,0.00000579194,0.001941221],"genre_scores_gemma":[0.9966872,0.000302946,0.0005637234,0.00003143191,0.0001504843,0.00001633808,0.00001777104,0.00002769716,0.002202347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1461764,"threshold_uncertainty_score":0.3301528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03840722605274943,"score_gpt":0.3474759199612021,"score_spread":0.3090686939084527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}