{"id":"W1928337022","doi":"10.1096/fasebj.29.1_supplement.507.2","title":"<i>Entamoeba histolytica</i> ‐Induced Caspase‐4/11 Activation Elicits a Pro‐Inflammatory Response in Macrophages","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammasome; Entamoeba histolytica; Caspase; Chemokine; Secretion; Caspase 1; Biology; Inflammation; Tumor necrosis factor alpha; Mucus; Pyroptosis; Cell biology; Cytokine; Immunology; Microbiology; Apoptosis; Programmed cell death; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002541612,0.0003893529,0.0003922775,0.000203627,0.000179368,0.0003670568,0.0001568981,0.0003587674,0.001946248],"category_scores_gemma":[0.0001858502,0.0001540117,0.0004612593,0.0001536495,0.0002612984,0.0002678069,0.0002422088,0.0006245691,0.0008257948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003157429,"about_ca_system_score_gemma":0.0001795412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002587711,"about_ca_topic_score_gemma":0.0002795471,"domain_scores_codex":[0.9997134,0.0000488103,0.00004796969,0.00004843286,0.0000540373,0.00008735235],"domain_scores_gemma":[0.9998715,0.00002089187,0.00004433345,0.00001717178,0.00002944164,0.00001659705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002131975,0.00002040456,0.0001980425,0.00007786249,0.000005402713,0.00006207929,0.00001115692,0.00001774447,0.9987586,0.00003396951,0.00007003653,0.0005316386],"study_design_scores_gemma":[0.00003490268,0.0004283919,0.007143135,0.00001631238,0.00002191099,0.0006652095,0.00007054013,0.0003832951,0.9883612,0.00007519656,0.002793123,0.00000673104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986774,0.002788212,0.004669679,0.0004503844,0.0001590656,0.000107365,0.001038817,0.0001524697,0.003860159],"genre_scores_gemma":[0.9890106,0.001302952,0.003058464,0.0004576327,0.00005704901,0.0001410839,0.001777881,0.00003068016,0.004163597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946248,"threshold_uncertainty_score":0.006510794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03833255793101618,"score_gpt":0.2936610781367529,"score_spread":0.2553285202057367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}