{"id":"W1929033929","doi":"10.1111/j.1365-2958.2010.07226.x","title":"Selective inactivation of SIDER2 retroposon‐mediated mRNA decay contributes to stage‐ and species‐specific gene expression in <i>Leishmania</i>","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Retroposon; Gene; Genetics; Gene expression; Synteny; Regulation of gene expression; Leishmania infantum; Context (archaeology); Untranslated region; Amastigote; Leishmania; Cell biology; Messenger RNA; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000190949,0.0003769159,0.0002305296,0.0001412057,0.00009743821,0.0003082273,0.0001840169,0.0002413119,0.0005449272],"category_scores_gemma":[0.0001757129,0.0001980741,0.0002803683,0.00008272033,0.0002240373,0.00014395,0.0002537015,0.0004169209,0.0002871444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001798738,"about_ca_system_score_gemma":0.0001320488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001839743,"about_ca_topic_score_gemma":0.000313412,"domain_scores_codex":[0.9998318,0.00003465225,0.00001756858,0.00004413545,0.00003623831,0.00003561363],"domain_scores_gemma":[0.9997481,0.00005405944,0.00009412062,0.00004207576,0.00002376812,0.00003794326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001260213,0.000001986608,0.00009856246,0.000005795842,9.876898e-7,0.00001472742,0.000003647393,0.000007141924,0.9996339,0.00001523064,0.000002003863,0.0002033737],"study_design_scores_gemma":[0.000003661307,0.0001212977,0.006795941,0.00000275646,0.000009834478,0.0004070967,0.00001711957,0.0004680222,0.9914576,0.00002417428,0.0006888984,0.000003576131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995821,0.0005484673,0.002956133,0.0000336891,0.0000062465,0.000009953541,0.0001014445,0.00007472642,0.0004484004],"genre_scores_gemma":[0.9970055,0.0002640772,0.001462518,0.00002711562,0.00000527856,0.00001183015,0.0003354059,0.00003634656,0.0008520839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005449272,"threshold_uncertainty_score":0.001823008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096682628106627,"score_gpt":0.2595573364736364,"score_spread":0.2485905101925702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}