{"id":"W1929033929","doi":"10.1111/j.1365-2958.2010.07226.x","title":"Selective inactivation of SIDER2 retroposon‐mediated mRNA decay contributes to stage‐ and species‐specific gene expression in <i>Leishmania</i>","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Retroposon; Gene; Genetics; Gene expression; Synteny; Regulation of gene expression; Leishmania infantum; Context (archaeology); Untranslated region; Amastigote; Leishmania; Cell biology; Messenger RNA; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003581049,0.0002121762,0.0005777564,0.0004321086,0.0000614329,0.00001427465,0.0001301064,0.0002458916,0.0000512698],"category_scores_gemma":[0.000714159,0.0001868983,0.00005788375,0.0005201007,0.0002789101,0.00005352078,0.0002079455,0.0005278358,0.00001459842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000163568,"about_ca_system_score_gemma":0.00008608607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005407808,"about_ca_topic_score_gemma":0.0001408449,"domain_scores_codex":[0.9983627,0.0001777494,0.0004119139,0.0004974398,0.000115723,0.0004344305],"domain_scores_gemma":[0.9987985,0.0002182311,0.0001290684,0.0003427667,0.0004006301,0.0001107308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004641292,0.0001358149,0.03306361,0.00003724007,0.00006413311,0.0000724007,0.000237074,0.000002112348,0.9639472,0.0002837049,0.001545818,0.0001467113],"study_design_scores_gemma":[0.001773305,0.0003891132,0.08083508,0.00005943636,0.00001072757,0.00003577481,0.0001389706,0.000003057667,0.9043758,0.00004550549,0.01219973,0.0001334898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948406,0.000717085,0.0009700648,0.001599433,0.0001139088,0.0008723808,0.00005517516,0.0000283501,0.0008030412],"genre_scores_gemma":[0.9965592,0.000198599,0.002421905,0.0004589123,0.00003632107,0.00004392135,0.0001022685,0.00002932147,0.0001495349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05957144,"threshold_uncertainty_score":0.7621491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096682628106627,"score_gpt":0.2595573364736364,"score_spread":0.2485905101925702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}