{"id":"W1929242319","doi":"10.1038/emboj.2011.96","title":"Constitutive heterochromatin reorganization during somatic cell reprogramming","year":2011,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Reprogramming; Somatic cell; Constitutive heterochromatin; Heterochromatin; Genetics; Cell biology; Chromatin; Cell; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003914514,0.00009791642,0.00008471674,0.00003766943,0.0003320385,0.00005314961,0.0002931487,0.00004932101,0.000105551],"category_scores_gemma":[0.00008326892,0.00006911695,0.00005920775,0.00008748271,0.0001115895,0.000007358285,0.0001341581,0.0001843231,0.00006064458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000248644,"about_ca_system_score_gemma":0.00006351613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004672147,"about_ca_topic_score_gemma":0.0000031462,"domain_scores_codex":[0.9990658,0.0001413849,0.0002107013,0.0001518973,0.0001788314,0.000251454],"domain_scores_gemma":[0.9994009,0.000008295343,0.0001357869,0.0002707549,0.0001016848,0.00008259687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000494962,0.00005654752,0.002171614,0.00002761562,0.00004522861,0.00004228307,0.0006619579,0.00002239546,0.996348,0.00002234824,0.0002081325,0.0003444278],"study_design_scores_gemma":[0.0004597533,0.0000981856,0.003605562,0.00003194163,0.00001820689,0.001006348,0.0004288956,0.00004467207,0.9935519,0.0002359471,0.0004016777,0.0001169189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905934,0.000325058,0.002565937,0.00006232532,0.0001180668,0.0001359501,0.000001111157,0.00001098246,0.006187113],"genre_scores_gemma":[0.9975612,0.000116011,0.001202718,0.00003167265,0.0001938404,0.000004147083,0.000004824404,0.00001718164,0.0008684563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006967693,"threshold_uncertainty_score":0.2818507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01758553374700465,"score_gpt":0.2352744140130683,"score_spread":0.2176888802660636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}