{"id":"W1929973469","doi":"10.1290/0510070.1","title":"MATRIX METALLOPROTEINASE-7 AND EPIDERMAL GROWTH FACTOR RECEPTOR MEDIATE HYPOXIA-INDUCED EXTRACELLULAR SIGNAL-REGULATED KINASE 1/2 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION AND SUBSEQUENT PROLIFERATION IN BLADDER SMOOTH MUSCLE CELLS","year":2006,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Cell biology; Mitogen-Activated Protein Kinase 3; Hypoxia (environmental); Kinase; Protein kinase A; MAPK/ERK pathway; Epidermal growth factor; Cell growth; Mitogen-activated protein kinase; Chemistry; Autophosphorylation; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004151277,0.0005584148,0.0005319844,0.0003083848,0.0001510241,0.00005988617,0.0001727503,0.000613082,0.00005357563],"category_scores_gemma":[0.0000647647,0.0005653247,0.00008894191,0.0003224398,0.0002159931,0.00005921831,0.0001658452,0.0003283001,0.000006679792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001472397,"about_ca_system_score_gemma":0.0002443819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006852051,"about_ca_topic_score_gemma":0.0001535962,"domain_scores_codex":[0.9968657,0.0003852503,0.0007741699,0.001053117,0.0002072417,0.000714456],"domain_scores_gemma":[0.9992171,0.00002898869,0.0002764411,0.0001996322,0.0001054373,0.0001724373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001105615,0.0002313826,0.001282511,0.00005030291,0.00005605375,0.00001989197,0.0001441619,0.000004107736,0.9946123,0.00004411833,0.00002638748,0.002423138],"study_design_scores_gemma":[0.002660431,0.0002631621,0.01803761,0.00003218465,0.00002212052,0.000008875251,0.00008710501,0.00008864051,0.9755099,0.00007656951,0.002565643,0.0006477362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948266,0.002867222,0.0001591967,0.0001289245,0.0002565022,0.001619908,0.00008183702,0.00003783314,0.00002203352],"genre_scores_gemma":[0.9951782,0.0001400544,0.002512541,0.00005569358,0.0003614032,0.0003029593,0.001231015,0.00006581788,0.000152297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01910241,"threshold_uncertainty_score":0.9996798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073632770771807,"score_gpt":0.2227090238019333,"score_spread":0.2119726960942152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}