{"id":"W1929973469","doi":"10.1290/0510070.1","title":"MATRIX METALLOPROTEINASE-7 AND EPIDERMAL GROWTH FACTOR RECEPTOR MEDIATE HYPOXIA-INDUCED EXTRACELLULAR SIGNAL-REGULATED KINASE 1/2 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION AND SUBSEQUENT PROLIFERATION IN BLADDER SMOOTH MUSCLE CELLS","year":2006,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Cell biology; Mitogen-Activated Protein Kinase 3; Hypoxia (environmental); Kinase; Protein kinase A; MAPK/ERK pathway; Epidermal growth factor; Cell growth; Mitogen-activated protein kinase; Chemistry; Autophosphorylation; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003966243,0.0004097109,0.0003841787,0.0005087933,0.000379011,0.0004050695,0.0003680331,0.0003651675,0.002051338],"category_scores_gemma":[0.0002964646,0.0004511364,0.0006662846,0.0002755661,0.0003258236,0.0004672351,0.0004825182,0.0008843194,0.0007907087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004393489,"about_ca_system_score_gemma":0.0004112641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001734839,"about_ca_topic_score_gemma":0.002068406,"domain_scores_codex":[0.9996172,0.00009276581,0.0000247925,0.00002340518,0.00007746129,0.000164375],"domain_scores_gemma":[0.9997594,0.00007149742,0.00002907862,0.00003327483,0.00002575665,0.00008103195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005400715,0.00008899828,0.0002634057,0.00007007801,0.00001139943,0.0001902979,0.00006843796,0.00005273164,0.9970912,0.0002991588,0.000100242,0.001224011],"study_design_scores_gemma":[0.00006867325,0.0004902022,0.01280666,0.000009336599,0.00003030492,0.0004589462,0.0001130732,0.001324578,0.982024,0.0001141322,0.00255211,0.000007876404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903978,0.004114881,0.002375799,0.0001507819,0.00006926616,0.00005672608,0.0002880731,0.00006865624,0.002477994],"genre_scores_gemma":[0.9894478,0.001707913,0.001814116,0.00006443606,0.00004345698,0.000119542,0.001079808,0.00001571697,0.005707162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002051338,"threshold_uncertainty_score":0.006862342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073632770771807,"score_gpt":0.2227090238019333,"score_spread":0.2119726960942152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}