{"id":"W1930968","doi":"10.2144/oct0211","title":"Isolation of Acetylcholinesterase from Apoptotic Human Lung Fibroblast Cells by Antibody Affinity Chromatography","year":2002,"lang":"en","type":"article","venue":"BioTechniques","topic":"Cholinesterase and Neurodegenerative Diseases","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"National Cancer Institute; National Institutes of Health; National Natural Science Foundation of China","keywords":"Acetylcholinesterase; Affinity chromatography; Cholinergic; Apoptosis; Molecular biology; Cell culture; Aché; Biology; Tacrine; Fibroblast; Acetylcholine; Biochemistry; Chemistry; Enzyme; Cell biology; In vitro; Pharmacology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005178071,0.0002326496,0.0003620624,0.0001805535,0.0000808507,0.00002756802,0.000102603,0.0001644399,0.0003215263],"category_scores_gemma":[0.00002348643,0.0002104491,0.0001888767,0.0002718247,0.0001003609,0.0001578222,0.00003965505,0.0001606618,0.00001058227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001962835,"about_ca_system_score_gemma":0.00001089458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009697324,"about_ca_topic_score_gemma":0.000003306275,"domain_scores_codex":[0.9987864,0.00007178732,0.0003952812,0.0003475055,0.0002135158,0.0001854663],"domain_scores_gemma":[0.9991302,0.00005066368,0.0001661976,0.0004132015,0.0001046952,0.0001350148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004316896,0.0005083716,0.006424667,0.00009950747,0.00003537483,0.000008515922,0.00009447854,6.70599e-7,0.9777083,0.000009945152,0.01495693,0.0001100523],"study_design_scores_gemma":[0.0006135012,0.0002031948,0.00686978,0.0003260088,0.0000988005,0.000004417317,0.00001118904,0.0003571483,0.9907784,0.00001142552,0.0005375925,0.0001885747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952532,0.0006833629,0.002612744,0.0001590645,0.00003858535,0.0004445692,0.0002933221,0.0002672317,0.0002479346],"genre_scores_gemma":[0.9954672,0.0003306534,0.003075274,0.0003530879,0.0001632782,0.00001549618,0.000474611,0.00003418042,0.00008622713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01441934,"threshold_uncertainty_score":0.8581864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02004566796276125,"score_gpt":0.2993067561234479,"score_spread":0.2792610881606866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}