{"id":"W1931940976","doi":"10.1111/j.1600-0765.2011.01450.x","title":"Cyclosporine‐A inhibits MMP‐2 and ‐9 activities in the presence of <i>Porphyromonas gingivalis</i> lipopolysaccharide: an experiment in human gingival fibroblast and U937 macrophage co‐culture","year":2012,"lang":"en","type":"article","venue":"Journal of Periodontal Research","topic":"Oral and gingival health research","field":"Health Professions","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministère de la Défense Nationale","keywords":"Porphyromonas gingivalis; Lipopolysaccharide; Matrix metalloproteinase; Zymography; U937 cell; In vitro; Macrophage; Microbiology; Inflammation; Fibroblast; Cell culture; Molecular biology; Chemistry; Immunology; Biology; Periodontitis; Internal medicine; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002924083,0.000364062,0.000296308,0.000184301,0.0001820077,0.0002627571,0.0001265856,0.0002404035,0.001002942],"category_scores_gemma":[0.0001365752,0.0001115518,0.000359296,0.0001738691,0.000185144,0.000146216,0.0001602742,0.0005732635,0.0002785329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001198668,"about_ca_system_score_gemma":0.0002563374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003915803,"about_ca_topic_score_gemma":0.0007417995,"domain_scores_codex":[0.9997677,0.00005960168,0.0000367943,0.00002937459,0.00005635391,0.00005014783],"domain_scores_gemma":[0.9998177,0.00004893836,0.00004271893,0.00002726377,0.00002613573,0.00003743206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003267752,0.0001200503,0.0002575614,0.00009000814,0.00000848433,0.00005984226,0.00001982129,0.00003016198,0.9979674,0.00001619009,0.00003316144,0.00107054],"study_design_scores_gemma":[0.00004914633,0.001983407,0.007169439,0.00001274993,0.00004184446,0.0003465974,0.00005768288,0.0004118637,0.9884773,0.00001346265,0.001431812,0.000004715432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951664,0.003007524,0.0007761061,0.0000943108,0.0000543204,0.00003298763,0.0001414152,0.00002854867,0.0006984486],"genre_scores_gemma":[0.9941659,0.002470369,0.001714436,0.00004683355,0.00005173635,0.00006478,0.0003283362,0.000007822426,0.001149661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001002942,"threshold_uncertainty_score":0.003355145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1555121571641964,"score_gpt":0.5287817316108326,"score_spread":0.3732695744466362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}