{"id":"W1932286144","doi":"10.1111/his.12723","title":"Impact of the 2013 <scp>A</scp>merican <scp>S</scp>ociety of <scp>C</scp>linical <scp>O</scp>ncology/<scp>C</scp>ollege of <scp>A</scp>merican <scp>P</scp>athologists guideline recommendations for human epidermal growth factor receptor 2 (<scp>HER</scp>2) testing of invasive breast carcinoma: a focus on tumours assessed as ‘equivocal’ for <scp>HER</scp>2 gene amplification by fluorescence <i>in‐situ</i> hybridization","year":2015,"lang":"en","type":"article","venue":"Histopathology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Capital District Health Authority; Dalhousie University","funders":"","keywords":"Medicine; Breast cancer; Internal medicine; Human Epidermal Growth Factor Receptor 2; Pathological; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","sts","open_science","research_integrity"],"consensus_categories":["metaepi_narrow","sts","research_integrity"],"category_scores_codex":[0.01219491,0.004749561,0.009288765,0.003679265,0.00185866,0.0003653911,0.006421613,0.004010085,0.00004216754],"category_scores_gemma":[0.2142429,0.004600408,0.00356415,0.00816656,0.007328403,0.001758523,0.002445134,0.005764114,0.0002048465],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.005579189,"about_ca_system_score_gemma":0.009376525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005487276,"about_ca_topic_score_gemma":0.001013228,"domain_scores_codex":[0.9625216,0.006325245,0.01134862,0.006942919,0.00500458,0.007857099],"domain_scores_gemma":[0.8940721,0.07110724,0.01337224,0.006243819,0.01162176,0.00358282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008199372,0.005826205,0.1232446,0.001806801,0.000708429,0.0002721378,0.01164037,0.0008707126,0.3651135,0.0006158065,0.4886255,0.00119389],"study_design_scores_gemma":[0.0334684,0.02755529,0.3403417,0.003015448,0.004256452,0.003871349,0.05471759,0.004136582,0.3726791,0.003348315,0.1517839,0.0008258637],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9500321,0.004640211,0.009595064,0.001199221,0.002998704,0.01287006,0.01052322,0.0008902217,0.007251187],"genre_scores_gemma":[0.9487028,0.002199636,0.02547136,0.001857428,0.002453225,0.00428884,0.006498264,0.001611691,0.006916752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3368416,"threshold_uncertainty_score":0.9994408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07644435501988396,"score_gpt":0.3636447140051723,"score_spread":0.2872003589852884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}