{"id":"W1932346107","doi":"10.1039/c5sc01767j","title":"In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)<sub>3</sub> and La(XT), for the treatment of bone resorption disorders","year":2015,"lang":"en","type":"article","venue":"Chemical Science","topic":"Lanthanide and Transition Metal Complexes","field":"Materials Science","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Vancouver Biotech (Canada); Saskatoon Medical Imaging; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Council for the Arts; Canadian Institutes of Health Research; University of Canterbury; California HIV/AIDS Research Program; Killam Trusts; Alexander von Humboldt-Stiftung","keywords":"Lanthanum; In vivo; Resorption; Ex vivo; Bone resorption; Chemistry; Medicine; Inorganic chemistry; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001917078,0.0002089715,0.0001798628,0.0001050514,0.0001226858,0.0001477908,0.0001602882,0.0002251659,0.001385653],"category_scores_gemma":[0.0001471761,0.0001287664,0.000158287,0.00007114223,0.0002376423,0.0002028324,0.00008459546,0.0003670861,0.0001770832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000151889,"about_ca_system_score_gemma":0.0001895306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004806414,"about_ca_topic_score_gemma":0.0005271052,"domain_scores_codex":[0.9999381,0.00001516882,0.000003103578,0.00001496447,0.00001495786,0.00001378412],"domain_scores_gemma":[0.9998986,0.00002663682,0.00002688312,0.000009613438,0.00001799358,0.0000202358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003199095,0.00004998655,0.0001799069,0.00002314119,0.000003836465,0.00001956477,0.000007798159,0.00007996876,0.9983768,0.00006923974,0.00002345501,0.0008464229],"study_design_scores_gemma":[0.00002012727,0.0009603924,0.001902931,0.000002240327,0.00001927495,0.0001476575,0.00002004454,0.0008830383,0.9950396,0.00005542482,0.0009442778,0.000005048858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902214,0.00192972,0.006042558,0.0001074091,0.00003553581,0.00003342349,0.0001779577,0.00004246121,0.001409537],"genre_scores_gemma":[0.9934175,0.0008929516,0.002619399,0.00007062896,0.00002327985,0.00003243497,0.0001370914,0.00002359163,0.002783144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001385653,"threshold_uncertainty_score":0.004635513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02852305698807037,"score_gpt":0.2782399664204503,"score_spread":0.2497169094323799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}