{"id":"W1932576728","doi":"10.1111/j.1399-0004.2004.00369.x","title":"Fine mapping of the X‐linked split‐hand/split‐foot malformation (SHFM2) locus to a 5.1‐Mb region on Xq26.3 and analysis of candidate genes","year":2004,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Congenital limb and hand anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; SickKids Foundation; Hospital for Sick Children","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Fogarty International Center; National Institutes of Health; Higher Education Commision, Pakistan; Higher Education Commission, Pakistan","keywords":"Candidate gene; Genetics; Syndactyly; Locus (genetics); Biology; Exon; X chromosome; Genetic linkage; Aplasia; Hypoplasia; Gene; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598801,0.0005059909,0.000203503,0.0006723205,0.0002624827,0.0001903451,0.0002585817,0.000349941,0.001614053],"category_scores_gemma":[0.0003344893,0.0001577934,0.0002072788,0.0002160075,0.0003639051,0.00007450982,0.0002960949,0.0002787909,0.0002362009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002042263,"about_ca_system_score_gemma":0.000139775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134663,"about_ca_topic_score_gemma":0.001732107,"domain_scores_codex":[0.9998412,0.00002824275,0.000009730125,0.00005244659,0.00004300025,0.00002525661],"domain_scores_gemma":[0.9998792,0.00004284784,0.00002750814,0.000006910096,0.000007367623,0.00003609702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006831111,0.000245387,0.05988936,0.0001367134,0.0001059452,0.02057974,0.0004151895,0.0007798736,0.8978895,0.0005954742,0.0002945032,0.01838521],"study_design_scores_gemma":[0.0004836708,0.001197112,0.8063804,0.000104144,0.000172411,0.06812286,0.0002903079,0.002923442,0.1119747,0.0005154373,0.007800581,0.0000349039],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979407,0.0003328518,0.00108097,0.00004393931,0.000004113057,0.00001710081,0.0001146693,0.00001272895,0.0004528453],"genre_scores_gemma":[0.9970185,0.000219883,0.001798425,0.00002827151,0.00001282889,0.00001987737,0.0002963721,0.000005903598,0.000599995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001614053,"threshold_uncertainty_score":0.005399585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03238065113738551,"score_gpt":0.3013422357695928,"score_spread":0.2689615846322073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}