{"id":"W1932584694","doi":"10.1161/circresaha.115.307004","title":"Bromodomain-Containing Protein 4","year":2015,"lang":"en","type":"article","venue":"Circulation Research","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research","keywords":"Cancer research; Survivin; microRNA; BRD4; Downregulation and upregulation; Apoptosis; Cell cycle; Bromodomain; Cell growth; Chemistry; Cell biology; Epigenetics; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001226383,0.00006506873,0.00005912274,0.00009513627,0.000110431,0.00005519862,0.0001382096,0.0001018874,0.00003551761],"category_scores_gemma":[0.0006423705,0.00006555809,0.00003270952,0.0002016811,0.00007829218,0.000007720211,0.00008832679,0.0001295805,0.0001202889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004273263,"about_ca_system_score_gemma":0.0002033659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004085633,"about_ca_topic_score_gemma":0.00001307883,"domain_scores_codex":[0.9987628,0.0002177641,0.0001337768,0.0002409233,0.0004083847,0.0002363867],"domain_scores_gemma":[0.9991474,0.00000840957,0.00002893518,0.0002785393,0.0003842152,0.0001525199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001434604,0.00006336779,0.01010591,0.00001352353,0.00002106955,0.000005567043,0.0001630209,0.0004005286,0.9678761,0.003837719,0.01096928,0.006400446],"study_design_scores_gemma":[0.003544159,0.001159097,0.02380157,0.00007038742,0.00000574814,0.00003579118,0.001323896,0.004171338,0.7065879,0.008756245,0.2498809,0.00066304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801038,0.0002187932,0.002997263,0.0004052995,0.00006347387,0.0004069761,0.000001784059,0.00001981874,0.01578283],"genre_scores_gemma":[0.9973966,0.000002321846,0.0004025372,0.00005475726,0.0002855622,0.00007220976,0.00007843408,0.00001467801,0.001692895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2612883,"threshold_uncertainty_score":0.2673381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1437878241753064,"score_gpt":0.3854728962561591,"score_spread":0.2416850720808527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}