{"id":"W1934086637","doi":"10.1002/jssc.201300511","title":"Purification and analysis of mono‐<scp>PEG</scp>ylated HSA by hydrophobic interaction membrane chromatography","year":2013,"lang":"en","type":"article","venue":"Journal of Separation Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; PEG ratio; Chromatography; Membrane; Elution; Lyotropic; Salt (chemistry); Hydrophobic effect; Gel permeation chromatography; Polyvinylidene fluoride; Hydrophilic interaction chromatography; High-performance liquid chromatography; Phase (matter); Organic chemistry; Biochemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002802185,0.0003385106,0.0002552205,0.0003351398,0.0002307759,0.0002767829,0.0002787957,0.0003034582,0.0007457404],"category_scores_gemma":[0.0002709659,0.0001166881,0.0002982705,0.0003115625,0.0001694996,0.0002655706,0.0001894226,0.0005966477,0.0008496054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574359,"about_ca_system_score_gemma":0.0002688268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009018845,"about_ca_topic_score_gemma":0.0007828525,"domain_scores_codex":[0.9998389,0.00002500665,0.00001665165,0.00002456429,0.00006852401,0.00002627371],"domain_scores_gemma":[0.9998742,0.00002683886,0.00001934569,0.00001804576,0.00004735686,0.00001417785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001918109,0.00001992617,0.0001234918,0.00003499527,0.000004798439,0.00003386182,0.00001250376,0.00007332116,0.9974086,0.00008329201,0.00005923013,0.002126876],"study_design_scores_gemma":[0.000001711607,0.00005181024,0.001440809,0.000003145969,0.000006523692,0.0001732923,0.000009867367,0.001626655,0.9944035,0.00006673574,0.002211658,0.000004348485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8209438,0.005213455,0.166124,0.0008440169,0.0001363274,0.0003396693,0.001598063,0.001002409,0.00379829],"genre_scores_gemma":[0.8532032,0.004397642,0.1287087,0.0004555259,0.0001065049,0.0002860333,0.004080591,0.0002407007,0.008521046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009018845,"threshold_uncertainty_score":0.002494752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106738724265321,"score_gpt":0.2857301828897166,"score_spread":0.2766234441654513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}