{"id":"W1934086637","doi":"10.1002/jssc.201300511","title":"Purification and analysis of mono‐<scp>PEG</scp>ylated HSA by hydrophobic interaction membrane chromatography","year":2013,"lang":"en","type":"article","venue":"Journal of Separation Science","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; PEG ratio; Chromatography; Membrane; Elution; Lyotropic; Salt (chemistry); Hydrophobic effect; Gel permeation chromatography; Polyvinylidene fluoride; Hydrophilic interaction chromatography; High-performance liquid chromatography; Phase (matter); Organic chemistry; Biochemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006674373,0.00007316824,0.0001543169,0.0003249322,0.00008357587,0.00007021629,0.0001805954,0.00005930817,0.00001789058],"category_scores_gemma":[0.0002029791,0.00006226867,0.00008331553,0.0009868505,0.0002246122,0.00008441142,0.00001989984,0.00006629277,0.00000239498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000170268,"about_ca_system_score_gemma":0.00007557209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001931084,"about_ca_topic_score_gemma":0.000003392442,"domain_scores_codex":[0.9989401,0.00005848205,0.0004393353,0.0001896655,0.000274115,0.00009836164],"domain_scores_gemma":[0.9984924,0.00002264205,0.0005642428,0.0002024953,0.0006254257,0.00009280049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007439938,0.00005144297,0.003328226,0.000004321211,0.00005732681,5.699751e-8,0.0001390076,0.0001470404,0.9951846,0.00001591044,0.0002292031,0.0008354461],"study_design_scores_gemma":[0.000177477,0.000151912,0.0825357,0.000004971839,0.00007259982,0.000008967085,0.0001678711,0.006173224,0.9085115,0.00005055793,0.002105433,0.00003981674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922658,0.000571662,0.006612351,0.0001131038,0.00006118632,0.0001270998,0.000005275243,0.00000293565,0.0002406262],"genre_scores_gemma":[0.9990181,0.0002937638,0.0005474978,0.00004150429,0.00001617878,0.000005874916,0.00001887366,0.000002733262,0.00005547979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08667311,"threshold_uncertainty_score":0.2539243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106738724265321,"score_gpt":0.2857301828897166,"score_spread":0.2766234441654513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}