{"id":"W1934286911","doi":"10.1016/j.lungcan.2015.09.004","title":"Analysis of serum protein levels of angiogenic factors and their soluble receptors as markers of response to cediranib in the NCIC CTG BR.24 clinical trial","year":2015,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; Princess Margaret Cancer Centre; Queen's University; Ottawa Hospital","funders":"Canadian Cancer Society Research Institute; Cancer Care Ontario; Cancer Research Institute","keywords":"Medicine; Internal medicine; Biomarker; Oncology; Proportional hazards model; Vascular endothelial growth factor; Gastroenterology; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00111152,0.000132936,0.0006017478,0.0002797233,0.0000198593,0.00000501764,0.0001063589,0.00008958502,0.0001702044],"category_scores_gemma":[0.0004004021,0.00007784594,0.0002477376,0.0009404757,0.00009678488,0.00004794696,0.00002973178,0.00009395897,4.835846e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001547863,"about_ca_system_score_gemma":0.0006626662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001859849,"about_ca_topic_score_gemma":0.0008524902,"domain_scores_codex":[0.9984815,0.0002932123,0.0005642084,0.0002231416,0.0002754853,0.0001624235],"domain_scores_gemma":[0.99888,0.0003029689,0.0002280091,0.0003187293,0.00015146,0.0001188601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1036423,0.0006980331,0.8537857,0.0001612779,0.007256038,0.000007449038,0.02096642,0.000207568,0.004490941,0.00004005163,0.002515777,0.006228423],"study_design_scores_gemma":[0.03570247,0.004365156,0.9359218,0.00036347,0.005212455,0.000001781286,0.006619652,0.0002488188,0.008633332,0.00005210412,0.002661065,0.0002179065],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961835,0.0008329162,0.00001652964,0.0008512507,0.000314784,0.001361968,0.0002046857,0.000006836873,0.0002275223],"genre_scores_gemma":[0.9988763,0.0000257224,0.0001004819,0.0001029726,0.0000488136,0.00008991053,0.00001001129,0.00001310595,0.0007327202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08213609,"threshold_uncertainty_score":0.3174466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07367530118651305,"score_gpt":0.4186572175267875,"score_spread":0.3449819163402744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}