{"id":"W1934356977","doi":"10.4049/jimmunol.182.1.675","title":"Heat Shock Proteins HSP27 and HSP70 Are Present in the Skin and Are Important Mediators of Allergic Contact Hypersensitivity","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Exercise and Physiological Responses","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; U.S. Department of Veterans Affairs; U.S. Department of Defense","keywords":"Heat shock protein; Dendritic cell; Hsp70; Epidermis (zoology); TLR4; Hsp27; Immunology; Immune system; Allergic contact dermatitis; Dermis; Oxazolone; Acquired immune system; Biology; Cell biology; Chemistry; Allergy; Anatomy; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008156172,0.0001089981,0.0004882382,0.0000726667,0.00004519633,0.000004612648,0.0001067389,0.00008954819,0.00001059749],"category_scores_gemma":[0.0003614358,0.00004766032,0.00006468088,0.00008736629,0.000177664,0.00003928663,0.0000338615,0.0003877769,4.540192e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001629828,"about_ca_system_score_gemma":0.00004756953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000518842,"about_ca_topic_score_gemma":0.00002469988,"domain_scores_codex":[0.9987751,0.0004544394,0.0003765743,0.0000747676,0.000160962,0.000158175],"domain_scores_gemma":[0.9988497,0.0006261191,0.0002291349,0.0001732606,0.00007891202,0.00004290579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02282983,0.001024928,0.0270521,0.00007995692,0.0003969708,0.001090778,0.006349117,0.00001359022,0.9272404,0.0002559857,0.0004398146,0.01322656],"study_design_scores_gemma":[0.001352049,0.002228667,0.9792715,0.0002047656,0.0000814478,0.001297587,0.003640538,0.00001999688,0.01089596,0.0006993137,0.0002521108,0.00005601207],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832587,0.008703835,0.000002155349,0.007653403,0.00003502556,0.0002582422,0.000003235242,0.000002474943,0.00008296771],"genre_scores_gemma":[0.9911945,0.008228967,0.00001492101,0.0004827383,0.00006266034,0.000001373359,5.029022e-7,0.000003745213,0.00001056805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9522194,"threshold_uncertainty_score":0.1943531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531662505073476,"score_gpt":0.2668367346492793,"score_spread":0.2515201095985445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}