{"id":"W1934816123","doi":"10.1111/j.1476-5381.2011.01448.x","title":"Changes in aldehyde dehydrogenase 2 expression in rat blood vessels during glyceryl trinitrate tolerance development and reversal","year":2011,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Aldehyde dehydrogenase; ALDH2; Vasodilation; Pharmacology; In vivo; Biotransformation; Blood vessel; Aorta; Drug tolerance; Chemistry; Medicine; Internal medicine; Biochemistry; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000170221,0.0003530806,0.0003039067,0.0002877166,0.0001446767,0.000227707,0.0001739351,0.0002708843,0.001250394],"category_scores_gemma":[0.0001495035,0.0001929731,0.0003632178,0.0001738623,0.0003598503,0.0002844266,0.0001600289,0.0006661923,0.0002663247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002066521,"about_ca_system_score_gemma":0.0001695379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005220857,"about_ca_topic_score_gemma":0.0005623552,"domain_scores_codex":[0.999894,0.00001539365,0.00000788873,0.00003061293,0.00001954111,0.00003250864],"domain_scores_gemma":[0.9997659,0.00002000794,0.00008723239,0.0000257212,0.00003432096,0.00006672488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008431023,0.00006198126,0.001064913,0.00002700563,0.000007965169,0.0001307679,0.00004742078,0.00002491111,0.9966434,0.00003289051,0.00001398639,0.001101684],"study_design_scores_gemma":[0.00003550309,0.002457886,0.05801363,0.000008194692,0.0000655839,0.0004078479,0.000214947,0.0005039418,0.9375398,0.00006965926,0.0006711372,0.0000119004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976822,0.0005640262,0.001104235,0.00002901353,0.0000232888,0.0000136311,0.000122143,0.00003749251,0.0004239352],"genre_scores_gemma":[0.9955504,0.0005871159,0.001063075,0.00004701812,0.00001862749,0.00005253726,0.0003489493,0.00001158168,0.002320649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001250394,"threshold_uncertainty_score":0.004182935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06382738687763265,"score_gpt":0.3381261805187153,"score_spread":0.2742987936410827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}