{"id":"W1935482859","doi":"10.3109/21691401.2015.1052467","title":"Drug delivery approaches for the treatment of glioblastoma multiforme","year":2015,"lang":"en","type":"review","venue":"Artificial Cells Nanomedicine and Biotechnology","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glioblastoma; Drug delivery; Medicine; Brain cancer; Drug; Brain tumor; Targeted drug delivery; Clinical trial; Blood–brain barrier; Population; Cancer; Pharmacology; Intensive care medicine; Bioinformatics; Nanotechnology; Internal medicine; Cancer research; Pathology; Central nervous system; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003628316,0.0006031745,0.001062562,0.003419485,0.0002657553,0.0005351438,0.000493137,0.0008717967,0.002697903],"category_scores_gemma":[0.0003845748,0.0001701554,0.0005433278,0.001895774,0.0002971083,0.0007537973,0.0004292058,0.0009155592,0.001182783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005202412,"about_ca_system_score_gemma":0.0007034728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001004627,"about_ca_topic_score_gemma":0.00199363,"domain_scores_codex":[0.9998342,0.00002461091,0.00002712653,0.00003106784,0.00006894753,0.00001408424],"domain_scores_gemma":[0.9998801,0.00004430175,0.00003300803,0.000002965457,0.00003081843,0.000008750487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007336476,0.0001100699,0.0001661422,0.04687528,0.0001232303,0.0004499124,0.00009152851,0.0003967832,0.01161245,0.003900307,0.0118093,0.9243916],"study_design_scores_gemma":[0.0000366146,0.0002615444,0.00129619,0.007811543,0.0002909772,0.004099616,0.00008105767,0.0002398373,0.005508801,0.001477742,0.9788639,0.00003221544],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002376125,0.9986091,0.0001862767,0.0001121782,0.00007678098,0.000009376943,0.00001515692,0.00000574119,0.000747758],"genre_scores_gemma":[0.002317548,0.9964502,0.0004272234,0.000123244,0.00006321004,0.00001550356,0.00002661005,0.000001754131,0.0005747085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003419485,"threshold_uncertainty_score":0.009025395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06164137989181644,"score_gpt":0.2810432739941147,"score_spread":0.2194018941022982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}