{"id":"W1936344549","doi":"10.1111/j.1468-1293.2011.00975.x","title":"Valproic acid in association with highly active antiretroviral therapy for reducing systemic <scp>HIV</scp>‐1 reservoirs: results from a multicentre randomized clinical study","year":2012,"lang":"en","type":"article","venue":"HIV Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; HIV Legal Network; University of British Columbia; Centre hospitalier universitaire de Québec; Ottawa Hospital; Centre Hospitalier de l’Université de Montréal; University of Ottawa; Royal Victoria Hospital; Canadian Institutes of Health Research; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; amfAR, The Foundation for AIDS Research","keywords":"Medicine; Antiretroviral therapy; Valproic Acid; Randomized controlled trial; Internal medicine; Therapeutic index; Human immunodeficiency virus (HIV); Viral load; Gastroenterology; Immunology; Pharmacology; Drug; Epilepsy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006473884,0.00158768,0.003224358,0.0005993213,0.000579848,0.001414794,0.001073334,0.002174864,0.002862609],"category_scores_gemma":[0.005548791,0.0008193334,0.002382676,0.0006807866,0.002003149,0.001085239,0.0004585299,0.001986595,0.0004377672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008287841,"about_ca_system_score_gemma":0.001410475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007486744,"about_ca_topic_score_gemma":0.001306099,"domain_scores_codex":[0.9950086,0.003809753,0.0003332506,0.0003228008,0.0002851771,0.0002403633],"domain_scores_gemma":[0.9959417,0.001757666,0.0009429354,0.0003756055,0.0002285916,0.0007535127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9757286,0.008054575,0.0008101649,0.0005324107,0.001154985,0.00003014559,0.00004339168,0.0001861267,0.002260043,0.00003109424,0.0001477864,0.01102068],"study_design_scores_gemma":[0.8628542,0.1329434,0.002483918,0.00004293691,0.0007546318,0.00003110148,0.00001477837,0.0002266678,0.0003967297,0.00003873113,0.0001994163,0.00001352249],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915122,0.004969864,0.0004386274,0.0003474331,0.0002726706,0.001676534,0.0002267845,0.0000413083,0.0005145332],"genre_scores_gemma":[0.9922315,0.003088403,0.001176069,0.0005150918,0.0005982557,0.001450368,0.0003041067,0.00001514614,0.0006210309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006473884,"threshold_uncertainty_score":0.03423756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03087288692689891,"score_gpt":0.3271519752171997,"score_spread":0.2962790882903008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}