{"id":"W1936727810","doi":"10.1002/stem.2036","title":"Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors","year":2015,"lang":"en","type":"article","venue":"Stem Cells","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Biology; Cell biology; Progenitor cell; Induced pluripotent stem cell; Stem cell; Myocyte; Embryonic stem cell; Myosin; Cellular differentiation; Population; Immunology; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001612143,0.0001994023,0.0004503966,0.00007110598,0.00003735629,0.00001079046,0.00008765315,0.000128229,0.0000203831],"category_scores_gemma":[0.000004513336,0.0001457003,0.00009019979,0.0001131906,0.00005180801,0.00003866743,0.00003621628,0.0001826035,0.00002638337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007114549,"about_ca_system_score_gemma":0.00006945413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005072541,"about_ca_topic_score_gemma":0.00000251163,"domain_scores_codex":[0.998643,0.00007346794,0.0003657384,0.0002756541,0.0004397958,0.0002022891],"domain_scores_gemma":[0.9991075,0.00002659816,0.0001249808,0.0003066817,0.0001849614,0.0002493102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006769326,0.0001478363,0.0001884069,0.0001749572,0.00009531993,0.00003769968,0.001371444,0.000127968,0.9958818,0.00005830454,0.0006800078,0.001168585],"study_design_scores_gemma":[0.001592303,0.0007198203,0.0003163293,0.0002454744,0.0001493141,0.000006949281,0.001535784,0.0005610633,0.9938527,0.00001028706,0.0008692195,0.0001407227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934515,0.002967135,0.001374095,0.0002055244,0.001043215,0.0006338735,0.00003706594,0.0001056094,0.0001820069],"genre_scores_gemma":[0.9943345,0.00001080234,0.0008152895,0.000008774467,0.0006782726,0.00002205939,0.00006578757,0.00003562848,0.004028903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003846896,"threshold_uncertainty_score":0.5941485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671447602745231,"score_gpt":0.2486813218133148,"score_spread":0.2219668457858625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}