{"id":"W1937690720","doi":"","title":"Computational modeling and biological evaluation of methylated (-)-EGCG analogs","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Proteasome; Methylation; Chemistry; Biochemistry; In vitro; In silico; Jurkat cells; Polyphenol; Apoptosis; Stereochemistry; Pharmacology; Biology; Antioxidant; T cell; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001560022,0.00004393417,0.0001236541,0.0001121851,0.00005132072,0.000007196014,0.00002983351,0.00005551038,0.0001232246],"category_scores_gemma":[0.000127686,0.00003284417,0.00001989548,0.0002315466,0.0001008496,0.00002269444,0.00002648361,0.0001447778,0.000003392372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008167236,"about_ca_system_score_gemma":0.0001874912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001246491,"about_ca_topic_score_gemma":0.00002241407,"domain_scores_codex":[0.9988324,0.0001795772,0.0001228457,0.0001458845,0.0005614826,0.0001578072],"domain_scores_gemma":[0.9991733,0.0001130204,0.00001721964,0.00007120885,0.0005770423,0.00004821815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001045785,0.0004742108,0.1148011,0.0004291951,0.0002262446,0.0000225115,0.0006433085,0.2900762,0.4767831,0.009224304,0.002769189,0.1035049],"study_design_scores_gemma":[0.002020728,0.0002870471,0.1216705,0.0001072841,0.00004250612,0.000006501193,0.00007338323,0.8507794,0.004317252,0.02057275,0.0000522405,0.00007038334],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946175,0.00321138,0.0005945481,0.0004312064,0.00002062299,0.0002841601,0.000006163358,0.00001133345,0.0008230621],"genre_scores_gemma":[0.9992926,0.00004976645,0.0004459456,0.00001771374,0.00009226309,0.00003553841,0.00003106876,0.000005298518,0.00002982048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5607032,"threshold_uncertainty_score":0.1884329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2862614193039835,"score_gpt":0.5011596679880385,"score_spread":0.214898248684055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}