{"id":"W1939098148","doi":"10.1002/mrd.22413","title":"Post‐ovulatory aging of oocytes disrupts kinase signaling pathways and lysosome biogenesis","year":2014,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kinexus Bioinformatics Corporation (Canada); University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development","keywords":"Biology; Cell biology; Signal transduction; Oocyte; Kinase; PI3K/AKT/mTOR pathway; Protein kinase A; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006875027,0.0001359103,0.0002462267,0.0001093035,0.0001081439,0.000007378942,0.00002738073,0.00006852827,0.00001109337],"category_scores_gemma":[0.0003094322,0.0001156658,0.00003320996,0.00009151518,0.0001509768,0.00004273125,0.00005853477,0.00007500801,0.000003100373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002464081,"about_ca_system_score_gemma":0.0000573284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001133402,"about_ca_topic_score_gemma":5.435575e-7,"domain_scores_codex":[0.9987395,0.0000777819,0.000275821,0.0006322438,0.0001323382,0.0001423106],"domain_scores_gemma":[0.9992936,0.00001350393,0.00008536692,0.0003529759,0.0001622379,0.00009236905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003222169,0.00008548908,0.03759078,0.0001594232,0.00007499829,0.000009052466,0.000627666,0.000003147902,0.9040394,0.0001406857,0.000006503261,0.05694059],"study_design_scores_gemma":[0.0003172577,0.00008010791,0.3561764,0.00003300124,0.00002471901,0.0000605106,0.0001051533,0.000006917719,0.6406891,0.0001007445,0.002308524,0.00009761369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945112,0.002986704,0.001494504,0.0005155914,0.0001355874,0.0002156534,0.00000115231,0.0000406366,0.00009890591],"genre_scores_gemma":[0.995262,0.00004833264,0.004346753,0.0001646493,0.00006437921,0.00001118866,0.00001777,0.0000114493,0.00007349205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3185856,"threshold_uncertainty_score":0.4716714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627590242986028,"score_gpt":0.2410443361660544,"score_spread":0.2247684337361941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}