{"id":"W1940767994","doi":"10.4049/jimmunol.164.3.1625","title":"Linear PADRE T Helper Epitope and Carbohydrate B Cell Epitope Conjugates Induce Specific High Titer IgG Antibody Responses","year":2000,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Epitope; Glycoconjugate; Polyclonal antibodies; Isotype; Monoclonal antibody; Linear epitope; Biochemistry; Antibody; Antigen; Biology; Molecular biology; Titer; Chemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001257539,0.0003766965,0.0007281917,0.000285487,0.0004646146,0.00003945739,0.0007300528,0.0004401043,0.003131378],"category_scores_gemma":[0.00008709357,0.0002457704,0.0001744625,0.0002339022,0.001089026,0.0002716334,0.0001145587,0.001160093,0.0007072242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004197661,"about_ca_system_score_gemma":0.0001424056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001568791,"about_ca_topic_score_gemma":0.000002949925,"domain_scores_codex":[0.9960589,0.002120781,0.0009079458,0.0002367027,0.00007728954,0.0005984274],"domain_scores_gemma":[0.9976352,0.001046265,0.0004809219,0.0006017543,0.0002057548,0.00003008707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009485901,0.0001702714,0.000352674,0.000008086338,0.0005019555,0.00004602319,0.00180034,0.000009441199,0.9693826,0.00007358058,0.0009329244,0.01723618],"study_design_scores_gemma":[0.004127743,0.002224004,0.02571327,0.0001154615,0.0001480287,0.002976779,0.0008833169,0.000001529261,0.6994612,0.0002612515,0.2636734,0.0004140077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8567024,0.1400223,0.00001967896,0.001617045,0.001182613,0.0001822447,0.00002097676,0.00002694778,0.0002257823],"genre_scores_gemma":[0.9213433,0.07000731,0.00009004932,0.00049014,0.0001437489,0.000003332188,0.00001622033,0.00004535822,0.007860517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2699214,"threshold_uncertainty_score":0.9999995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033138991632735,"score_gpt":0.238924869358272,"score_spread":0.2285934794419447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}