{"id":"W1940768002","doi":"10.1186/s12935-015-0231-z","title":"Etoposide induces cell death via mitochondrial-dependent actions of p53","year":2015,"lang":"en","type":"article","venue":"Cancer Cell International","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research","keywords":"Etoposide; Programmed cell death; Mitochondrion; Cancer research; Apoptosis; Cell; Medicine; Cell biology; Biology; Neuroscience; Genetics; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009966749,0.000127684,0.0002120377,0.0001003219,0.00003914989,0.00001725764,0.0002100601,0.00006285753,0.0008477692],"category_scores_gemma":[0.00006862891,0.0001106851,0.00008698575,0.00008779115,0.00007403598,0.0001480418,0.0001202053,0.0001994107,0.00005182839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009388618,"about_ca_system_score_gemma":0.0005265821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002362757,"about_ca_topic_score_gemma":0.0003157858,"domain_scores_codex":[0.9985114,0.00002617894,0.0002551683,0.0002476434,0.0007602096,0.0001993823],"domain_scores_gemma":[0.9987955,0.00005307396,0.0001270592,0.0002010016,0.0006383706,0.0001850006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001139187,0.0009949128,0.04331173,0.0002879528,0.0008095314,0.00007203394,0.003213726,0.0004149489,0.8380778,0.0004869626,0.1074528,0.003738374],"study_design_scores_gemma":[0.005615246,0.0004398203,0.009689273,0.0001813865,0.0001973319,0.00002667458,0.001289112,0.0004124926,0.8927718,0.000487399,0.08859583,0.000293591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7000944,0.003941909,0.001087783,0.003750341,0.005126083,0.0007030457,0.0001580514,0.00008068592,0.2850577],"genre_scores_gemma":[0.9781772,0.000684682,0.0009019725,0.0002143926,0.0009683279,0.0001368779,0.00002986066,0.00002118624,0.01886545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2780829,"threshold_uncertainty_score":0.9282478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08949637099171534,"score_gpt":0.3952874771036114,"score_spread":0.3057911061118961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}