{"id":"W1942361731","doi":"10.4049/jimmunol.1103717","title":"Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Immunogenicity; Tropism; Biology; Virology; Recombinant DNA; Serotype; Viral vector; T cell; Vaccination; Adenoviridae; CD8; Immune system; Immunology; Virus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007867898,0.0001570151,0.0002056541,0.00006129646,0.0001504266,0.00001580769,0.0003755789,0.000212036,0.00002513537],"category_scores_gemma":[0.000157713,0.0001070392,0.00006567769,0.0000868846,0.0001556725,0.000008740518,0.0001358147,0.0004479002,0.00003086752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002555787,"about_ca_system_score_gemma":0.00009438645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000276325,"about_ca_topic_score_gemma":0.0000118804,"domain_scores_codex":[0.9986414,0.0005129075,0.000230147,0.0001038832,0.0001546587,0.0003569663],"domain_scores_gemma":[0.9991246,0.0001567793,0.000194892,0.0003319893,0.0001180597,0.00007362028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006789001,0.0001248354,0.0008086272,0.000006647677,0.0002175951,0.000001655884,0.0001964805,0.000003767147,0.9862972,0.00000193283,0.0009404824,0.004611698],"study_design_scores_gemma":[0.001380496,0.007420706,0.00316043,0.00001032252,0.00003315604,0.0001056701,0.00005490007,0.000002220024,0.9823266,0.00001409811,0.005377863,0.0001135074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669709,0.03220692,0.00001748089,0.0002562756,0.0003200565,0.0001413385,0.000003835034,0.000003887272,0.00007929731],"genre_scores_gemma":[0.9968019,0.002439492,0.00002935511,0.0003094405,0.0002405875,0.000002501626,0.000005563361,0.00002520477,0.0001459864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02983096,"threshold_uncertainty_score":0.4364933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02059835176264788,"score_gpt":0.2739177717176115,"score_spread":0.2533194199549636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}