{"id":"W1942540255","doi":"10.1055/s-0037-1613205","title":"Protease-Activated Receptors Upregulate Cyclooxygenase-2 Expression in Human Endothelial Cells","year":2002,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"British Heart Foundation","keywords":"Thrombin; Prostacyclin; Umbilical vein; Downregulation and upregulation; Thrombomodulin; Protein C; Receptor; Thrombin receptor; Protease-activated receptor 2; Agonist; Proinflammatory cytokine; Protease-activated receptor; Endothelial stem cell; Protease; Endothelium; Serine protease; Chemistry; Cell biology; Molecular biology; Biology; Endocrinology; Inflammation; Immunology; Biochemistry; Platelet; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001606455,0.0003022854,0.000577471,0.0002282807,0.0002221977,0.00004923325,0.00009214693,0.0002095873,0.002559208],"category_scores_gemma":[0.00001855831,0.0002656924,0.0001132383,0.000340788,0.0001016759,0.0001744898,0.00007074525,0.0002537846,0.0000519589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000049867,"about_ca_system_score_gemma":0.00001381298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008135537,"about_ca_topic_score_gemma":0.000009759002,"domain_scores_codex":[0.9981986,0.0001134985,0.0004447529,0.0005059448,0.0003352774,0.0004019161],"domain_scores_gemma":[0.9991384,0.00003289625,0.0001340869,0.0003924641,0.00004344581,0.0002587355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005403716,0.0005385474,0.001835145,0.00006889471,0.0000584562,0.000009963011,0.0006970565,0.000005537097,0.9878507,0.0002156505,0.001187208,0.007478822],"study_design_scores_gemma":[0.00361076,0.0002860977,0.01477531,0.0003277235,0.00009245303,0.00001053131,0.0002147556,0.0002909138,0.9774445,0.0002022449,0.002432775,0.0003119558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948899,0.000153853,0.00005626236,0.0008606656,0.0001704605,0.0009048156,0.00002839564,0.0001553813,0.002780238],"genre_scores_gemma":[0.9964611,0.0004376263,0.002011141,0.0003906867,0.00009516685,0.00006894477,0.00003043281,0.00005605609,0.0004488664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01294016,"threshold_uncertainty_score":0.9999796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06769915077888153,"score_gpt":0.2984015043633533,"score_spread":0.2307023535844718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}