{"id":"W1942540255","doi":"10.1055/s-0037-1613205","title":"Protease-Activated Receptors Upregulate Cyclooxygenase-2 Expression in Human Endothelial Cells","year":2002,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"British Heart Foundation","keywords":"Thrombin; Prostacyclin; Umbilical vein; Downregulation and upregulation; Thrombomodulin; Protein C; Receptor; Thrombin receptor; Protease-activated receptor 2; Agonist; Proinflammatory cytokine; Protease-activated receptor; Endothelial stem cell; Protease; Endothelium; Serine protease; Chemistry; Cell biology; Molecular biology; Biology; Endocrinology; Inflammation; Immunology; Biochemistry; Platelet; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002113722,0.0001824197,0.000231333,0.0002805532,0.0001413847,0.0004528647,0.00007003113,0.0001686436,0.002079449],"category_scores_gemma":[0.0003407178,0.0001492044,0.0002311542,0.000210576,0.0000841389,0.0001509088,0.000137426,0.0003010781,0.0006340877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001742827,"about_ca_system_score_gemma":0.0001311584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005168653,"about_ca_topic_score_gemma":0.000636857,"domain_scores_codex":[0.9997097,0.00007487506,0.00002464272,0.00002830647,0.00008098504,0.00008143517],"domain_scores_gemma":[0.999846,0.00004869119,0.00002701457,0.00002810743,0.00002919395,0.00002099477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003123593,0.00005210458,0.000374979,0.00005099548,0.000008822921,0.0002237653,0.00003620886,0.00003141737,0.9951816,0.00009613561,0.0001884951,0.003443098],"study_design_scores_gemma":[0.00007094843,0.001121642,0.01914376,0.0000152837,0.00005778583,0.00114979,0.00009217907,0.0009341743,0.9675905,0.0001031116,0.009710949,0.000009801689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980438,0.009989128,0.003980948,0.0002232031,0.0001611131,0.0000657588,0.0006100163,0.0001049419,0.004427004],"genre_scores_gemma":[0.9872923,0.004709829,0.002728869,0.0001461743,0.0001236843,0.00005167989,0.0008057375,0.0000128459,0.00412878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002079449,"threshold_uncertainty_score":0.006956458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06769915077888153,"score_gpt":0.2984015043633533,"score_spread":0.2307023535844718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}