{"id":"W1944016236","doi":"10.1016/j.ceca.2007.02.001","title":"A quantitative model for linking <mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" altimg=\"si1.gif\" overflow=\"scroll\"><mml:msup><mml:mrow><mml:mtext>Na</mml:mtext></mml:mrow><mml:mrow><mml:mo>+</mml:mo></mml:mrow></mml:msup><mml:mo>/</mml:mo><mml:msup><mml:mrow><mml:mtext>Ca</mml:mtext></mml:mrow><mml:mrow><mml:mn>2</mml:mn><mml:mo>+</mml:mo></mml:mrow></mml:msup></mml:math> exchanger to SERCA during refilling of the sarcoplasmic reticulum to sustain <mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" altimg=\"si2.gif\" overflow=\"scroll\"><mml:mrow><mml:mo stretchy=\"false\">[</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mtext>Ca</mml:mtext></mml:mrow><mml:mrow><mml:mn>2</mml:mn><mml:mo>+</mml:mo></mml:mrow></mml:msup></mml:mrow><mml:mo stretchy=\"false\">]</mml:mo></mml:mrow></mml:math> oscillations in vascular smooth muscle","year":2007,"lang":"lv","type":"article","venue":"Cell Calcium","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Endoplasmic reticulum; SERCA; Calcium signaling; Biophysics; Cytoplasm; Chemistry; Calcium; Physics; Algorithm; Computer science; ATPase; Nuclear magnetic resonance; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002946479,0.001155405,0.0007881149,0.002015366,0.0009905258,0.003725284,0.003099043,0.003346321,0.03708349],"category_scores_gemma":[0.009656216,0.0008875803,0.002549031,0.001343615,0.001703786,0.005680348,0.001304733,0.002159837,0.007232021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004288802,"about_ca_system_score_gemma":0.003180297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01795195,"about_ca_topic_score_gemma":0.01403998,"domain_scores_codex":[0.998585,0.0004129088,0.00009239593,0.00044,0.000295464,0.0001743111],"domain_scores_gemma":[0.9963839,0.00204674,0.0003443671,0.0003379987,0.0006894864,0.0001974592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001225413,0.0001578258,0.001714396,0.0003100036,0.0001096803,0.0002730012,0.0003671757,0.3208278,0.004374981,0.6274958,0.0172168,0.02703004],"study_design_scores_gemma":[0.00003278681,0.00004683345,0.0004815879,0.00004973718,0.00004133329,0.00008878075,0.00007906315,0.7268693,0.0007517897,0.2565663,0.01494626,0.00004616483],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.009488103,0.0002849455,0.954855,0.002975941,0.0002073222,0.0001880019,0.002780009,0.001379019,0.02784168],"genre_scores_gemma":[0.4347938,0.001474286,0.4483648,0.001289645,0.0002414196,0.002367012,0.006222683,0.001466249,0.10378],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03708349,"threshold_uncertainty_score":0.1240566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02049269030825155,"score_gpt":0.2508989625255582,"score_spread":0.2304062722173066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}