{"id":"W1944670301","doi":"10.2460/ajvr.76.6.507","title":"Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae–or zymosan-challenged pigs","year":2015,"lang":"en","type":"article","venue":"American Journal of Veterinary Research","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Zoetis","keywords":"Efferocytosis; Proinflammatory cytokine; Zymosan; Inflammation; Leukotriene B4; Bronchoalveolar lavage; Actinobacillus pleuropneumoniae; Phagocytosis; Immunology; Apoptosis; Medicine; Lung; Biology; In vitro; Macrophage; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002298236,0.0003993623,0.0004264165,0.0002498659,0.0001237679,0.0002197961,0.0001807976,0.0004283385,0.0007549307],"category_scores_gemma":[0.0001616079,0.0001580916,0.0003026613,0.00008751594,0.0002578372,0.0002518487,0.0001477803,0.0005347466,0.0001952129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001686184,"about_ca_system_score_gemma":0.0001478046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002672712,"about_ca_topic_score_gemma":0.0004683745,"domain_scores_codex":[0.9997867,0.00006027998,0.0000239712,0.00003333599,0.00003384213,0.00006189956],"domain_scores_gemma":[0.9998697,0.00002450517,0.00004292903,0.00001139292,0.00001383737,0.0000376772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000901831,0.0001084838,0.0003670202,0.00004919716,0.000004744825,0.00007110708,0.0000181086,0.00002458025,0.9973744,0.000006506035,0.00001103967,0.00106295],"study_design_scores_gemma":[0.0001699011,0.01232172,0.0460889,0.00003387287,0.00008754455,0.0004474121,0.0001298968,0.0008739374,0.9387236,0.00002551173,0.001084883,0.00001286464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984633,0.0009221816,0.0002266677,0.00003685502,0.00001191893,0.00001683071,0.00007155687,0.00001086379,0.0002398759],"genre_scores_gemma":[0.9974501,0.0007585706,0.0005566431,0.00006328657,0.00002180446,0.00004073769,0.0002310438,0.000004285466,0.0008735642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007549307,"threshold_uncertainty_score":0.002525449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08739851056376373,"score_gpt":0.3579987882524123,"score_spread":0.2706002776886485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}