{"id":"W1945063075","doi":"10.1039/c3dt51940f","title":"H<sub>6</sub>phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with<sup>89</sup>Zr,<sup>111</sup>In and<sup>177</sup>Lu","year":2013,"lang":"en","type":"article","venue":"Dalton Transactions","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"TRIUMF; University of British Columbia","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Chelation; Chemistry; Conjugate; Trastuzumab; Bifunctional; Immunoconjugate; Radiochemistry; Nuclear chemistry; Antibody; Monoclonal antibody; Biochemistry; Cancer; Medicine; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003400766,0.0007891738,0.0008566877,0.0003460609,0.0005820298,0.0001260083,0.0003092741,0.0005335125,0.002377803],"category_scores_gemma":[0.00005320792,0.0007336679,0.0003692008,0.001292611,0.00057652,0.0005026956,0.00001832691,0.001579955,0.0004430411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004567644,"about_ca_system_score_gemma":0.0005213122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003351707,"about_ca_topic_score_gemma":0.00002411808,"domain_scores_codex":[0.9957674,0.0001109088,0.0009483389,0.00126698,0.0008499795,0.00105645],"domain_scores_gemma":[0.9971104,0.0004848572,0.0001595399,0.0008611685,0.0003111819,0.001072902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005059009,0.01225015,0.01694137,0.003139653,0.003131233,0.0003885107,0.005824142,0.3746264,0.4848025,0.00168856,0.009278527,0.08286995],"study_design_scores_gemma":[0.01532728,0.0009803599,0.0129923,0.000607269,0.001486772,0.0006344023,0.003353606,0.2789118,0.6375734,0.0005281885,0.04545099,0.002153581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682783,0.0007837277,0.01998028,0.007014277,0.00006932992,0.001764643,0.0003542898,0.0004406424,0.001314466],"genre_scores_gemma":[0.993066,0.0004147833,0.001992407,0.001338851,0.00027309,0.001398113,0.0004334689,0.0001463841,0.000936932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.152771,"threshold_uncertainty_score":0.9995114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133132595067266,"score_gpt":0.2494430409678614,"score_spread":0.2361297814611348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}