{"id":"W1945063075","doi":"10.1039/c3dt51940f","title":"H<sub>6</sub>phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with<sup>89</sup>Zr,<sup>111</sup>In and<sup>177</sup>Lu","year":2013,"lang":"en","type":"article","venue":"Dalton Transactions","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"TRIUMF; University of British Columbia","funders":"National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Chelation; Chemistry; Conjugate; Trastuzumab; Bifunctional; Immunoconjugate; Radiochemistry; Nuclear chemistry; Antibody; Monoclonal antibody; Biochemistry; Cancer; Medicine; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148242,0.0003993991,0.0001381541,0.0001177587,0.00006986484,0.0001970187,0.0002172058,0.0002380199,0.001209592],"category_scores_gemma":[0.0001006715,0.0001101863,0.0001076916,0.0001265821,0.0001943289,0.0001345674,0.0002136916,0.0001867347,0.0006995308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002917826,"about_ca_system_score_gemma":0.0001575858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006607273,"about_ca_topic_score_gemma":0.0007886209,"domain_scores_codex":[0.9999201,0.0000128762,0.00000532196,0.00001797013,0.00002646746,0.00001721719],"domain_scores_gemma":[0.9999588,0.000004666532,0.00001160605,0.000003794855,0.000008973572,0.00001223966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073752,0.000007809201,0.000163802,0.00005449453,0.000003985994,0.00005603835,0.000009650646,0.0001018648,0.9970349,0.00009121669,0.00007232121,0.002296478],"study_design_scores_gemma":[0.00001107486,0.0001564403,0.001098985,0.000002809653,0.000009879101,0.0002244364,0.000006876994,0.0004664084,0.9948238,0.00001644074,0.003179617,0.000003332749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808354,0.00136005,0.01153494,0.0001154554,0.0000305747,0.00008284674,0.0004882602,0.0002096711,0.005342811],"genre_scores_gemma":[0.9882779,0.0006728615,0.006435318,0.00006387594,0.00001100787,0.00004646281,0.0004947264,0.00003193662,0.003965999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001209592,"threshold_uncertainty_score":0.0040465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133132595067266,"score_gpt":0.2494430409678614,"score_spread":0.2361297814611348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}