{"id":"W1945848574","doi":"10.1016/j.pediatrneurol.2015.07.005","title":"Synthetic ACTH Is Not Superior to Prednisolone for Infantile Spasms: Randomized Clinical Trials and Tribulations","year":2015,"lang":"en","type":"letter","venue":"Pediatric Neurology","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Prednisolone; Medicine; Randomized controlled trial; Adrenocorticotropic hormone; Pediatrics; Psychology; Internal medicine; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006973393,0.0004549951,0.003945746,0.0004818352,0.00009891341,0.00004427405,0.0001896833,0.001214249,0.000240557],"category_scores_gemma":[0.02999325,0.0003308305,0.0008010786,0.0002278518,0.0002381657,0.00003886452,0.0001530011,0.001502001,0.0001453748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003088072,"about_ca_system_score_gemma":0.0006962884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004312193,"about_ca_topic_score_gemma":0.000004533653,"domain_scores_codex":[0.9929012,0.003035089,0.001746575,0.001035818,0.0004960439,0.0007852572],"domain_scores_gemma":[0.9755008,0.02245325,0.0004385606,0.000708657,0.0003459476,0.0005527479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.09659046,0.0001817283,0.006055632,0.0002316256,0.0003895601,0.0004057729,0.00007307943,5.96088e-7,0.000004075371,0.000004868986,0.8946427,0.001419893],"study_design_scores_gemma":[0.2181386,0.006154921,0.00140559,0.00001523885,0.00584359,0.0002605072,0.00000237849,0.0002493961,0.00001742123,0.0003699206,0.7671719,0.0003705485],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1200397,0.001326369,0.0003107662,0.8666327,0.00113559,0.009205512,0.001116607,0.00009362133,0.0001391519],"genre_scores_gemma":[0.05763578,0.006812854,0.001589983,0.8974235,0.02669794,0.004324335,0.001272638,0.0002348209,0.004008118],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1274708,"threshold_uncertainty_score":0.9999143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1202558420194148,"score_gpt":0.4295813217204548,"score_spread":0.30932547970104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}